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You searched on: Topic Area: Life Sciences Research

Displaying records 51 to 60 of 153 records.
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51. The Role of Water in the Thermodynamics of Drug Binding to Cyclodextrin
Topic: Life Sciences Research
Published: 7/1/2007
Authors: Niya Tordorova, Frederick P. Schwarz
Abstract: The thermodynamic parameters, DBGo, DBHo, and DBSo, of the drugs flurbiprofen (FLP), nabumetone (NAB), and naproxen (NPX) binding to b-cyclodextrin (bCD) and to g-cyclodextrin (gCD) in 0.10 M sodium phosphate buffer were determined from isothermal ti ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830570

52. Human Polymorphic Variants of the NEIL1 DNA Glycosylase: Potential Implications for Human Health
Topic: Life Sciences Research
Published: 5/25/2007
Authors: Laura Roy, Pawel Jaruga, Thomas Wood, Amanda K McCullough, M Miral Dizdar, R. Stephen Lloyd
Abstract: In mammalian cells, the repair of DNA bases damaged by reactive oxygen species is primarily initiated by a series of DNA glycosylases that include OGG1, NTH1, NEIL1 and NEIL2. To explore the functional significance of NEIL1, we recently reported tha ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830533

53. The Stiffness of Collagen Fibrils Influences Vascular Smooth Muscle Cell Phenotype
Topic: Life Sciences Research
Published: 3/1/2007
Authors: Dennis P. McDaniel, Gordon Allan Shaw, John T Elliott, Kiran Bhadriraju, Curtis W Meuse, Koo-Hyun Chung, Anne L Plant
Abstract: Cells receive signals from the extracellular matrix through receptor-dependent interactions, but they are also influenced by the mechanical properties of the matrix. While bulk properties of substrates have been shown to effect cell behavior, we sho ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830514

54. Repair of Formamidopyrimidines in DNA Involves Different Glycosylases - Role of the OGG1, NTH1, and NEIL1 Enzymes
Topic: Life Sciences Research
Published: 12/9/2005
Authors: J Hu, N de Souza-Pinto, K Haraguchi, Barbara A Hogue, Pawel Jaruga, M M Greenberg, M Miral Dizdar, V. Bohr
Abstract: 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 4,6-diamino-5-formamidopyrimidine (FapyA), are formed abundantly in DNA of cultured cells or tissues exposed to ionizing radiation or to other free radical-generating systems. We show here that ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830498

55. Mitochondrial DNA as a cancer biomarker
Topic: Life Sciences Research
Published: 5/1/2005
Authors: J P. Jakupciak, W. Wang, Maura E Markowitz, D Ally, Michael D Coble, Sudhir Srivastava, A Maitra, Peter E. Dr. Barker, David Sidransky, Catherine D O'Connell
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=906449

56. Infrared and Raman Spectroscopy Characterization of Biological Products
Topic: Life Sciences Research
Published: 1/1/2005
Author: Vytautas Reipa
Abstract: Both infrared and Raman are increasingly applied in biomolecular structure characterization, thus getting acceptance alongside traditional bioanalytical techniques. Physical principles and biological sampling requirements are reviewed. Advanced appli ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830440

57. Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA
Topic: Life Sciences Research
Published: 12/21/2004
Authors: Pawel Jaruga, M Birincioglu, T A Rosenquist, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903209

58. Extrinsic factors potassium chloride and glycerol induce thermostability in recombinant anthranilate synthase from Archaeoglobus fulgidus
Topic: Life Sciences Research
Published: 12/1/2004
Authors: W M. Byrnes, V L. Vilker
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=906583

59. Reversible Proton Transfer Dynamics in Bacteriorhodopsin
Topic: Life Sciences Research
Published: 8/20/2004
Authors: Y. S. Lee, Morris Krauss
Abstract: Proton transfer in bacteriorhodopsin from the cytoplasm to the extracellular side is initiated from protonated asp96 in the cytoplasmic region towards the deprotonated Schiff base. This occurs in the transition from the photocycle late M state to th ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830451

60. MitoMorphy: An Alignment and Annotation Tool for Human Mitochondrial DNA Polymorphisms
Topic: Life Sciences Research
Published: 8/1/2004
Authors: Veerasamy Ravichandran, Ram D Sriram, G L. Gilliland
Abstract: MitoMorphy uses a number of publicly available human mitochondrial DNA sequences from different ethnic groups to compare and annotate the associated polymorphic data. It provides an integrated display of mitochondrial DNA sequence comparison, sequenc ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830431



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