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You searched on: Topic Area: Life Sciences Research

Displaying records 21 to 30 of 144 records.
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21. Hyperspectral Imaging and Analysis of Single Erythrocytes
Topic: Life Sciences Research
Published: 8/12/2011
Authors: Ji Y. Lee, Matthew Lawrence Clarke, Fuyuki Tokumasu, John F. Lesoine, David W Allen, Robert C. Chang, Maritoni Abatayo Litorja, Jeeseong Hwang
Abstract: We report a hyperspectral imaging and analysis technique to resolve unique physico-chemical characteristics of subcellular substances in single erythrocytes. We constructed a microscope system installed with a spectral light engine capable of contr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908693

22. Combinatorial Screening of Hydrogel Scaffolds for 3D Cell Culture
Topic: Life Sciences Research
Published: 5/2/2011
Authors: Kaushik Chatterjee, Marian F Young, Carl George Simon Jr.
Abstract: Optimizing cell-material interactions is critical towards maximizing regeneration in tissue engineering. Combinatorial and high-throughput (CHT) methods can be used to systematically screen tissue scaffolds to identify optimal biomaterial properties ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903763

23. A General Model for the Dynamics of Cell Volume, Global Stability, and Optimal Control
Topic: Life Sciences Research
Published: 2/11/2011
Author: James D. Benson
Abstract: Cell volume and concentration regulation in the presence of changing extracellular environments has been studied for centuries, and recently a general nondimensional model was introduced that encompassed solute and solvent transmembrane flux for a wi ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904647

24. Melting Point Equations for the Ternary System Water/Sodium Chloride/Ethylene Glycol Revisited
Topic: Life Sciences Research
Published: 12/1/2010
Authors: James D. Benson, Aniruddha Bagchi, Xu Han, John K Critser, Erik J Woods
Abstract: Partial phase diagrams are of considerable utility in the development of optimized cryobiological procedures. Recent theoretical predictions of the melting points of ternary solutions of interest to cryobiology have caused us to re-examine measurment ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=905323

25. The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo
Topic: Life Sciences Research
Published: 3/16/2010
Authors: Minin Liu, Viswanath Bandaru, Jeffrey Bond, Pawel Jaruga, Xiaobei Zhao, Plamen P Christov, Cynthia Burrows, Carmelo J. Rizzo, M Miral Dizdar, Susan Wallace
Abstract: To protect cells from oxidative DNA damage and mutagenesis, organisms possess multiple glycosylases to recognize the damaged bases and to initiate the Base Excision Repair (BER) pathway. Recently, three DNA glycosylases were identified in mammals tha ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903370

26. Evidence for the involvement of DNA repair enzyme NEIL1 in nucleotide excision repair of (5'R)- and (5'S)-8,5'-Cyclo-2'-deoxyadenosines
Topic: Life Sciences Research
Published: 2/16/2010
Authors: Pawel Jaruga, Yan Xiao, Vladimir Vartanian, R Stephen Lloyd, M Miral Dizdar
Abstract: The DNA repair enzyme NEIL1 is a DNA glycosylase that is involved in the first step of base excision repair (BER) of oxidatively induced DNA damage. NEIL1 exhibits a strong preference for excision of 4,6-diamino-5-formamidopyrimidine (FapyAde) and 2, ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904755

27. The oxidative DNA glycosylases of Mycobacterium tuberculosis exhibit different substrate specificities from their Escherichia coli counterparts
Topic: Life Sciences Research
Published: 2/4/2010
Authors: Yin Guo, Viswanath Bandaru, Pawel Jaruga, Xiaobei Zhao, Cynthia Burrows, Shigenori Iwai, M Miral Dizdar, Jeffrey Bond, Susan Wallace
Abstract: The DNA glycosylases function in the first step of the base excision repair process that is responsible for removing endogenous oxidative purine and pyrimidine damages from DNA. The DNA glycosylases that remove oxidized DNA bases fall into two genera ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904173

28. In-plane Homogeneity and Lipid Dynamics in tethered Bilayer Lipid Membranes (tBLMs)
Topic: Life Sciences Research
Published: 1/1/2010
Authors: Siddharth Shenoy, Radu Moldovan, James Fitzpatrick, David J. Vanderah, Markus Deserno, Mathias Losche
Abstract: Tethered bilayer lipid membranes (tBLMs) were prepared by the self-assembly of thiolated lipidic anchors on gold films sputtered on Si wafers, followed by phospholipid precipitation via rapid solvent exchange. They were characterized in their in-plan ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903881

29. Quantitative Infrared Spectroscopy of Formalin-Fixed, Paraffin-Embedded Tissue Specimens: Paraffin Wax Removal with Organic Solvents
Report Number: 832407
Topic: Life Sciences Research
Published: 12/1/2009
Authors: Curtis W Meuse, Peter E. Dr. Barker
Abstract: Formalin-fixed, paraffin embedded tissue specimens for histopathology are cut to 3-20 μm thickness to allow transmission of light, and optimize tissue morphology. Tissue is stabilized by formalin fixation followed by impregnation with wax in non ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832407

30. Substrate specificity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase
Topic: Life Sciences Research
Published: 9/1/2009
Authors: Viktoriya Sidorenko, Arthur P Grollman, Pawel Jaruga, M Miral Dizdar, Dmitry Zharhov
Abstract: Human 8-oxoguanine-DNA-glycosylase (OGG1) efficiently removes mutagenic 8-oxoguanine (8-oxoGua) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyGua) when paired with cytosine in damaged DNA. Excision of 8-oxoGua mispaired with adenine may lead t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=902113



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