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You searched on: Topic Area: Medical Devices Sorted by: title

Displaying records 11 to 20 of 28 records.
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11. Machine Learning Analysis for Identification of Cell Shape Metrics Associated with Stem Cell Differentiation in Nanofiber Scaffolds
Topic: Medical Devices
Published: 4/19/2014
Authors: Desu Chen, Sumona Sarkar, Stephen J Florczyk, Subhadip Bodhak, Carl George Simon Jr., Joy P Dunkers, Julian Candia, Wolfgang Losert
Abstract: Cell shape has been demonstrated to be closely related to cell function and may be an important predictor of cell fate. Many metrics are available to describe cell shape, however the relationship of these metrics to cell fate are not well understood ...

12. Medical Applications of Nano-electrotechnologies: Challenges and Concerns for Technology Roadmaps, International Standards and Measurements
Topic: Medical Devices
Published: 9/23/2010
Author: Herbert S Bennett
Abstract: This paper presents reasons why standards are important for medical applications of nano-electrotechnologies and summarizes ongoing consensus-based international technology roadmapping and standards activities. It gives key results from a recent int ...

13. Microfabricated multispectral MRI agents: a brief overview
Topic: Medical Devices
Published: 9/3/2009
Author: Gary Zabow
Abstract: This paper provides an introductory overview on recent top-down microfabricated, as opposed to traditional bottom-up chemically synthesized, magnetic resonance imaging (MRI) contrast agents. As a specific example of the enhanced agent functionality ...

14. Microfluidic Based Contactless DielectrophoreticDevice: Modeling and Analysis
Topic: Medical Devices
Published: 9/1/2010
Authors: Saugandhika Minnikanti, Darwin R Reyes-Hernandez, Ruben Claudio Aguilar, Joseph Pancrazio, Michael Gaitan, Nathalia Peixoto
Abstract: While there have been many attempts at patterning cells onto substrates, a reliable method for trapping cell clusters and forming cell arrays in a predefined geometry remains to be demonstrated. We intend to develop a multielectrode array platfor ...

15. Morphological Changes Driven by Nanofibrous Scaffolds Induce Marrow Stromal Cell Osteogenesis
Topic: Medical Devices
Published: 10/11/2011
Authors: Carl George Simon Jr., Kaushik Chatterjee, Christopher K. Tison, Girish Kumar, Patrick S Pine, Marc L Salit, Jennifer H McDaniel, Marian F Young
Abstract: Cells are sensitive to tissue scaffold architecture and these cell-material interactions drive cell functions critical in tissue regeneration. Results presented here demonstrate that nanofiber scaffolds force primary human bone marrow stromal cells ...

16. On-chip CO2 control for microfluidic cell culture
Topic: Medical Devices
Published: 1/1/2011
Authors: Samuel P Forry, Laurie E Locascio
Abstract: Carbon dioxide partial pressure (PCO2) was controlled on-chip by flowing pre-equilibrated aqueous solutions through control channels across the device. Elevated PCO2 (e.g. 0.05 atm) was modulated in neighboring stagnant channels via equilibration th ...

17. Optimization of Next-Generation Sequencing Informatics Pipelines for Clinical Laboratory Practice
Topic: Medical Devices
Published: 7/8/2015
Authors: Justin M Zook, Amy Gargis, Lisa Kalman, Ira Lubin, Marc L Salit
Abstract: We direct your readers' attention to the principles and guidelines (see Supplementary Guidelines) developed by the Next-generation Sequencing: Standardization of Clinical Testing II (Nex-StoCT II) informatics workgroup, which was convened by the Cent ...

18. Predicting Microstructure Development During Casting of Drug Eluting Coatings
Topic: Medical Devices
Published: 9/19/2010
Authors: David M. Saylor, Jonathan E Guyer, Daniel Wheeler, James A Warren
Abstract: We have devised a novel diffuse interface formulation to model the development of chem- ical and physical inhomogeneities, i.e. microstructure, during the process of casting drug eluting coatings. These inhomogeneities, which depend on the ...

19. Predictive Gold Nanocluster Formation Controlled by Metal-Ligand Complexes
Topic: Medical Devices
Published: 1/9/2012
Authors: John M Pettibone, Jeffrey W Hudgens
Abstract: The formation of ligand-protected transition metal nanoclusters in size-selective syntheses is driven by the inherent properties of the protecting ligands. We have previously reported the selective, monodisperse product formation of phosphine protect ...

20. Quantifying and Improving Clinical-grade Coverage and Accuracy using Augmented Exome Sequencing
Topic: Medical Devices
Published: 7/16/2015
Authors: Justin M Zook, Anil Patwardhan, Marc L Salit, Carlos Bustamante, Euan Ashley, Michael Snyder, John West, Richard Chen
Abstract: Exome sequencing is increasingly used for the clinical evaluation of genetic disease, yet accuracy and coverage in medically interpretable parts of the genome remains under-characterized. We evaluate recently developed exome sequencing platforms in t ...

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