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Displaying records 11 to 20 of 25 records.
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11. Medical Applications of Nano-electrotechnologies: Challenges and Concerns for Technology Roadmaps, International Standards and Measurements
Topic: Medical Devices
Published: 9/23/2010
Author: Herbert S Bennett
Abstract: This paper presents reasons why standards are important for medical applications of nano-electrotechnologies and summarizes ongoing consensus-based international technology roadmapping and standards activities. It gives key results from a recent int ...

12. Microfluidic Based Contactless DielectrophoreticDevice: Modeling and Analysis
Topic: Medical Devices
Published: 9/1/2010
Authors: Saugandhika Minnikanti, Darwin R Reyes-Hernandez, Ruben Claudio Aguilar, Joseph Pancrazio, Michael Gaitan, Nathalia Peixoto
Abstract: While there have been many attempts at patterning cells onto substrates, a reliable method for trapping cell clusters and forming cell arrays in a predefined geometry remains to be demonstrated. We intend to develop a multielectrode array platfor ...

13. Morphological Changes Driven by Nanofibrous Scaffolds Induce Marrow Stromal Cell Osteogenesis
Topic: Medical Devices
Published: 10/11/2011
Authors: Carl George Simon Jr., Kaushik Chatterjee, Christopher K. Tison, Girish Kumar, Patrick S Pine, Marc L Salit, Jennifer H McDaniel, Marian F Young
Abstract: Cells are sensitive to tissue scaffold architecture and these cell-material interactions drive cell functions critical in tissue regeneration. Results presented here demonstrate that nanofiber scaffolds force primary human bone marrow stromal cells ...

14. On-chip CO2 control for microfluidic cell culture
Topic: Medical Devices
Published: 1/1/2011
Authors: Samuel P Forry, Laurie E Locascio
Abstract: Carbon dioxide partial pressure (PCO2) was controlled on-chip by flowing pre-equilibrated aqueous solutions through control channels across the device. Elevated PCO2 (e.g. 0.05 atm) was modulated in neighboring stagnant channels via equilibration th ...

15. Optimization of Next-Generation Sequencing Informatics Pipelines for Clinical Laboratory Practice
Topic: Medical Devices
Published: 7/8/2015
Authors: Justin M Zook, Amy Gargis, Lisa Kalman, Ira Lubin, Marc L Salit
Abstract: We direct your readers' attention to the principles and guidelines (see Supplementary Guidelines) developed by the Next-generation Sequencing: Standardization of Clinical Testing II (Nex-StoCT II) informatics workgroup, which was convened by the Cent ...

16. Predicting Microstructure Development During Casting of Drug Eluting Coatings
Topic: Medical Devices
Published: 9/19/2010
Authors: David M. Saylor, Jonathan E Guyer, Daniel Wheeler, James A Warren
Abstract: We have devised a novel diffuse interface formulation to model the development of chem- ical and physical inhomogeneities, i.e. microstructure, during the process of casting drug eluting coatings. These inhomogeneities, which depend on the ...

17. Predictive Gold Nanocluster Formation Controlled by Metal-Ligand Complexes
Topic: Medical Devices
Published: 1/9/2012
Authors: John M Pettibone, Jeffrey W Hudgens
Abstract: The formation of ligand-protected transition metal nanoclusters in size-selective syntheses is driven by the inherent properties of the protecting ligands. We have previously reported the selective, monodisperse product formation of phosphine protect ...

18. Quantifying and Improving Clinical-grade Coverage and Accuracy using Augmented Exome Sequencing
Topic: Medical Devices
Published: 7/16/2015
Authors: Justin M Zook, Anil Patwardhan, Marc L Salit, Carlos Bustamante, Euan Ashley, Michael Snyder, John West, Richard Chen
Abstract: Exome sequencing is increasingly used for the clinical evaluation of genetic disease, yet accuracy and coverage in medically interpretable parts of the genome remains under-characterized. We evaluate recently developed exome sequencing platforms in t ...

19. Roles of Nanofiber Structure and Chemistry in Directing Stem Cell Morphology, Differentiation and Gene Expression
Topic: Medical Devices
Published: 4/19/2014
Authors: Sumona Sarkar, Bryan A. Baker, Desu Chen, Wolfgang Losert, Carl George Simon Jr., Joy P Dunkers
Abstract: Nanofiber technology has emerged as a promising tool to recapitulate the native extracellular matrix (ECM) environment for tissue engineering and regenerative medicine strategies. Cell-material interactions in the nanofiber system are largely de ...

20. Standards for Plasma and Serum Protoemics in Early Cancer Detection: A Needs Assessment Report From the NIST-NCI SMART Workshop, August 18-19, 2005
Topic: Medical Devices
Published: 9/1/2006
Authors: Peter E. Dr. Barker, Paul D Wagner, Stephen E Stein, David M Bunk, S Srivastava, Gilbert Omenn
Abstract: The National Institute of Standards and Technology (NIST) and the National Cancer Institute (NCI) co-sponsored a workshop on August 18-19, 2005 to examine needs for reference materials to support biomarker discovery for early cancer detection. Needs ...

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