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Topic Area: Drugs/Pharmaceuticals
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Displaying records 21 to 30 of 54 records.
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21. Integrated Plastic Microfluidic Devices with ESI-MS for Drug Screening and Residue Analysis
Topic: Drugs/Pharmaceuticals
Published: 5/1/2001
Authors: Y. Jiang, P-C. Wang, Laurie E Locascio, C S. Lee
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904419

22. Isolation, Purification, and Full NMR Assignments of cyclopamine from Veratrum californicum
Topic: Drugs/Pharmaceuticals
Published: 6/24/2009
Authors: Daniel W Bearden, John E. Oatis, Pam Brunsfeld, James W. Rushing, Peter D. Moeller, Thomas N. Gallien, George W. Cooper
Abstract: The Hedgehog (Hh) signaling pathway is essential for embryogenesis and tissue homeostasis in the adult. However, it may also induce malignancies in a number of tissues when constitutively activated, and it also may have a role in other forms of nor ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832291

23. Membrane protein resistance of oligo(ethylene oxide) self-assembled monolayers
Topic: Drugs/Pharmaceuticals
Published: 7/31/2017
Authors: David J Vanderah, Marlon L Walker, David Travis Gallagher, Ryan Vierling, Fay Crawshaw
Abstract: Spectroscopic ellipsometry was used to evaluate the resistance to protein adsorption (RPA) of self- assembled monolayers (SAMs) of HS(CH2)3O(CH2CH2O)6M and [HS(CH2)3CH]2O-(CH2CH2O)6M, where M = CH3 or H, on Au. The SAMs were exposed to fibrinogen ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913472

24. Microfluidic Remote Loading for Rapid Single-Step Liposomal Drug Preparation
Topic: Drugs/Pharmaceuticals
Published: 7/29/2014
Authors: Wyatt N Vreeland, Renee R Hood, Don L. DeVoe
Abstract: Here we report a microfluidic system that enables rapid and efficient remote loading of amphipathic drugs into nanoscale liposomes, combining liposome synthesis and remote drug loading in a continuous integrated process. Unlike established bulk m ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915563

25. Microfluidic Synthesis of Nano-Liposomal Anesthetics
Topic: Drugs/Pharmaceuticals
Published: 5/12/2013
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Mariana Junqueira, Julia Finkel, Don L. DeVoe
Abstract: Topical anesthesia has the ability to provide painless application of pain management medications for minor procedures such as venipuncture, particularly in the pediatric population. Liposomes have been proposed as a highly advantageous nanocarrier f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913770

26. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Topic: Drugs/Pharmaceuticals
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913538

27. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Topic: Drugs/Pharmaceuticals
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915017

28. Modification of tethered bilayers by phospholipid exchange with vesicles
Topic: Drugs/Pharmaceuticals
Published: 2/27/2013
Authors: David J Vanderah, Rima Budvytyte, Mindaugas Mickevicius, Gintaras Valincius, Frank Heinrich
Abstract: Phosphatidylcholine and cholesterol exchange between vesicles and planar tethered bilayer lipid membranes (tBLMs) was demonstrated from electrochemical impedance spectroscopy (EIS), fluorescence microscopy (FM), and neutron reflectometry (NR) data. ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912490

29. Monte Carlo and dynamics simulations of cdk5 Kinase inhibitor peptides p5 in aqueous solution
Topic: Drugs/Pharmaceuticals
Published: 7/20/2012
Authors: Antonio Cardone, Sergio Hassan, Mary C Brady, Ram D Sriram, Harish C. Pant
Abstract: Protein function depends on shape changes that are triggered by interactions with other molecules. Insights into protein dynamics and interactions enable the understanding of certain pathologies, which may be caused by the deregulation of protein ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911466

30. Multicomponent Chemical Imaging of Pharmaceutical Solid Dosage Forms with Broadband CARS Microscopy
Topic: Drugs/Pharmaceuticals
Published: 7/15/2013
Authors: Christopher Michael Hartshorn, Marcus T Cicerone, Young Jong Lee, Charles H Camp, John Heddleston, Patrick Marsac, Tim Rhodes, Zhen Liu, Nicole Canfield
Abstract: We compare broadband coherent anti-Stokes Raman scattering (BCARS) microscopy with spontaneous Raman microscopy for quantitative and qualitative assessment of multicomponent pharmaceuticals. Indomethacin was used as a model active pharmaceutical ingr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913135



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