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Displaying records 21 to 30 of 32 records.
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21. Predictive Gold Nanocluster Formation Controlled by Metal-Ligand Complexes
Topic: Drugs/Pharmaceuticals
Published: 1/9/2012
Authors: John M Pettibone, Jeffrey W Hudgens
Abstract: The formation of ligand-protected transition metal nanoclusters in size-selective syntheses is driven by the inherent properties of the protecting ligands. We have previously reported the selective, monodisperse product formation of phosphine protect ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908225

22. Probing the Nature of Ibuprofen Confined in Mesoporous Media by Neutron Vibrational Spectroscopy and First-Principles Calculations
Topic: Drugs/Pharmaceuticals
Published: 5/15/2012
Author: Ken Kangyi Qian
Abstract: {B}Purpose{/B}: In this paper, the nature of ibuprofen incorporated into both mesoporous silicon dioxide and magnesium aluminometasilicate by sublimation and adsorption was investigated using neutron vibrational spectroscopy. {B}Methods{/B}: Crystall ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910370

23. Quantification of Drugs of Abuse in Municipal Wastewater via SPE and Direct Injection Liquid Chromatography Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Michele M Schantz, Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904046

24. Quantifying Dithiothreitol Displacement of Functional Ligands from Gold Nanoparticles
Topic: Drugs/Pharmaceuticals
Published: 10/27/2012
Authors: De-Hao D. Tsai, Frank W DelRio, Sherrie R. Elzey, Suvajyoti S. Guha, Michael Russel Zachariah, Vincent A Hackley, Melanie P Shelton
Abstract: Dithiothreitol (DTT)-based displacement is widely utilized for separating ligands from their gold nanoparticle (AuNP) conjugates, a critical step for differentiating and quantifying surface-bound functional ligands and therefore the effective surface ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911354

25. Quantitation of HER2 and Telomerase Biomarkers in Solid Tumors with IgY Antibodies and Nanocrystal Detection
Topic: Drugs/Pharmaceuticals
Published: 5/15/2008
Authors: Yan Xiao, X Gao, G Gannot, M Emmert-Buck, S Srivastava, Paul D Wagner, Michael D. Amos, Peter E. Dr. Barker
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901234

26. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912782

27. Recent Advances in Electrochemical Glyco-biosensing
Topic: Drugs/Pharmaceuticals
Published: 4/8/2011
Authors: Rebecca A Zangmeister, Germarie Sanchez-Pomales
Abstract: Biosensors based on electrochemical transduction mechanisms have recently made advances into the field of glycan analysis. These glyco-biosensor assays offer simple, rapid, sensitive and economical approaches to the measurement need for rapid glycan ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908197

28. Standards for the Optical Detection of Protein Particulates
Topic: Drugs/Pharmaceuticals
Published: 1/23/2012
Authors: Dean C Ripple, Michael J Carrier, Joshua R. Wayment
Abstract: Particulates in protein therapeutics, composed of agglomerated protein monomers, may cause an immunogenic response in patients. Consequently, industry and the FDA desire more accurate methods for counting and characterizing particulates. Unlike lik ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908731

29. Structural Calcium (Trypsin, Subtilisin)
Topic: Drugs/Pharmaceuticals
Published: Date unknown
Authors: G L. Gilliland, A Teplyakov
Abstract: There are about 40 families of serine proteases defined by amino acid sequence similarities that can be further grouped into 7 clans on the basis of their tertiary structure and the order of the catalytic triad.^u1^ Members of clans SA and SB are c ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830437

30. Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7552
Topic: Drugs/Pharmaceuticals
Published: 1/15/2009
Authors: Antonio Cardone, Ram D Sriram, Wayne Albers, Harish C. Pant
Abstract: A high-affinity inhibitor protein called CIP, which can be produced by small truncations of p35, was earlier identified by Amin, Albers, and Pant. P35 is one of the physiological activators of cdk5, a member of the cyclin-dependent kinase family. The ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901184



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