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You searched on: Topic Area: Drugs/Pharmaceuticals Sorted by: title

Displaying records 1 to 10 of 34 records.
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1. A Lectin-Based Gold Nanoparticle Assay for Probing Glycosylation of Glycoproteins
Topic: Drugs/Pharmaceuticals
Published: 4/17/2012
Authors: Germarie Sanchez-Pomales, Todd A. Morris, James Falabella, Michael J Tarlov, Rebecca A Zangmeister
Abstract: We report a glycoanalysis method in which lectins are used to probe the glycans of glycoproteins that are adsorbed on gold nanoparticles. A model mannose-presenting glycoprotein, ribonuclease B (RNase B), and the therapeutic monoclonal antibody (mAb) ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=909549

2. A Streamlined Hydrolysis Procedure for the LC/MS/MS Analysis of Cocaine in Wastewater Samples
Topic: Drugs/Pharmaceuticals
Published: 1/2/2012
Authors: Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We report a streamlined procedure for the routine analysis of cocaine in municipal wastewater. By adding NaOH (to 0.025 M) and incubating wastewater samples at 55 °C for two hours, cocaine and its principal metabolites are quantitatively converted i ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903657

3. An Average Enumeration Method of Hyperspectral Imaging Data for Quantitative Evaluation of Medical Device Surface Contamination
Topic: Drugs/Pharmaceuticals
Published: 9/15/2014
Authors: Hanh Le, Moon Kim, Jeeseong Hwang, Yi Yang, Pawneena U-Thainual, Jin Kang, Do-Hyun Kim
Abstract: We propose a quantification method called Mapped Average Principal component analysis Score (MAPS) to enumerate the contamination coverage on common medical device surfaces. The method was adapted from conventional Principal Component Analysis (P ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916392

4. An International Effort to Achieve Comparability of Test Results
Topic: Drugs/Pharmaceuticals
Published: 12/16/2006
Authors: C Jackson, Robert Wielgosz, Willie E May
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901211

5. An interlaboratory comparison of sizing and counting of subvisible particles mimicking protein aggregates
Topic: Drugs/Pharmaceuticals
Published: 11/24/2014
Authors: Dean C Ripple, Christopher B Montgomery, Zhishang Hu
Abstract: Accurate counting and sizing of protein particles has been limited by discrepancies of counts obtained by different methods. To understand the bias and repeatability of techniques in common use in the biopharmaceutical community, the National Institu ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915231

6. Breast Cancer Biomarker Measurements and Standards
Topic: Drugs/Pharmaceuticals
Published: 1/24/2013
Authors: Kenneth D Cole, Lili Wang, Hua-Jun He
Abstract: Cancer is a heterogeneous disease characterized by changes in the levels and activities of important cellular proteins, including oncogenes and tumor suppressors. Genetic mutations cause changes in protein activity and protein expression levels that ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912867

7. Cellular Biomarkers Used to Detect Damage in Tissue-Engineered Medical Products
Topic: Drugs/Pharmaceuticals
Published: 5/1/2002
Author: H Rodriguez
Abstract: Tissue engineering is an emerging new area of biotechnology that will provide replacement tissues for patients, as well as complex, functional biological systems for research and testing in the pharmaceutical industry. However, a lack of a formal re ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830298

8. Color Test Reagents/Kits for Preliminary Identification of Drugs of Abuse
Topic: Drugs/Pharmaceuticals
Published: 7/1/2000
Author: Alim A Fatah
Abstract: The objective of this standard is to establish minimum requirements for color test reagent/kits to detect drugs. It is applicable to field testing kits that consist of color reagents for the preliminary identification of drugs. It does not apply to k ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=30166

9. Critical Examination of the Colloidal Particle Model of Globular Proteins
Topic: Drugs/Pharmaceuticals
Published: 2/3/2015
Authors: Prasad Srinivasan Sarangapani, Steven D Hudson, Ronald Leland Jones, Jack F Douglas, Jai Avinash Pathak
Abstract: Recent studies of globular protein solutions have uniformly adopted a colloidal view of proteins as particles, a perspective that neglects the polymeric primary structure of these biological macromolecules, their intrinsic flexibility and their abi ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915903

10. Effects of Desialylation on Human alpha1-Acid Glycoprotein-Ligand Interactions
Topic: Drugs/Pharmaceuticals
Published: 9/16/2013
Authors: Richard Y. Huang, Jeffrey W Hudgens
Abstract: Human α1-Acid Glycoprotein (AGP), an acute phase glycoprotein, exists predominantly in blood. With its ability to bind basic, lipophilic, and acidic drugs, AGP has served as a drug carrier. It has been shown that the carbohydrate composition of ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914495



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