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You searched on: Topic Area: Drugs/Pharmaceuticals Sorted by: date

Displaying records 11 to 20 of 55 records.
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11. Effects of Desialylation on Human alpha1-Acid Glycoprotein-Ligand Interactions
Topic: Drugs/Pharmaceuticals
Published: 9/16/2013
Authors: Richard Y. Huang, Jeffrey W Hudgens
Abstract: Human α1-Acid Glycoprotein (AGP), an acute phase glycoprotein, exists predominantly in blood. With its ability to bind basic, lipophilic, and acidic drugs, AGP has served as a drug carrier. It has been shown that the carbohydrate composition of ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914495

12. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses
Topic: Drugs/Pharmaceuticals
Published: 9/12/2013
Authors: John P Marino, Katharine Therese Briggs, Heather Cohen, Katya Ravid, Simon C. Robson, David M. Mosser
Abstract: Sepsis is a highly fatal disease caused by an initial hyperinflammatory response followed by a state of profound immunosuppression. Although it is well appreciated that the initial production of proinflammatory cytokines by macrophages accompanies th ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912870

13. Multicomponent Chemical Imaging of Pharmaceutical Solid Dosage Forms with Broadband CARS Microscopy
Topic: Drugs/Pharmaceuticals
Published: 7/15/2013
Authors: Christopher Michael Hartshorn, Marcus T Cicerone, Young Jong Lee, Charles H Camp, John Heddleston, Patrick Marsac, Tim Rhodes, Zhen Liu, Nicole Canfield
Abstract: We compare broadband coherent anti-Stokes Raman scattering (BCARS) microscopy with spontaneous Raman microscopy for quantitative and qualitative assessment of multicomponent pharmaceuticals. Indomethacin was used as a model active pharmaceutical ingr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913135

14. The Metrology of Counting Protein Particles
Topic: Drugs/Pharmaceuticals
Published: 7/13/2013
Authors: Dean C Ripple, Michael J Carrier, Richard E Cavicchi, Christopher B Montgomery, Zhishang Hu
Abstract: A common degradation pathway for protein-based drugs is the growth of protein aggregates or particles. Counting and characterization of these particles is needed to assure the quality, efficacy, and safety of this type of drug. The unusual physic ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=916139

15. Microfluidic Synthesis of Nano-Liposomal Anesthetics
Topic: Drugs/Pharmaceuticals
Published: 5/12/2013
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Mariana Junqueira, Julia Finkel, Don L. DeVoe
Abstract: Topical anesthesia has the ability to provide painless application of pain management medications for minor procedures such as venipuncture, particularly in the pediatric population. Liposomes have been proposed as a highly advantageous nanocarrier f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913770

16. Quantitative Analysis of Dendron-Conjugated Cisplatin-Complexed Gold Nanoparticles Using Scanning Particle Mobility Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 5/8/2013
Authors: De-Hao D. Tsai, Tae Joon Cho, Sherrie R. Elzey, Julien C. Gigault, Vincent A Hackley
Abstract: We report a high-resolution and traceable method to quantify the drug loading on nanoparticle-based cancer therapeutics, and demonstrate this method using a model cisplatin functionalized dendron-gold nanoparticle (AuNP) conjugate. Electrospray diffe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912782

17. The Metrology of Counting Protein Particles
Topic: Drugs/Pharmaceuticals
Published: 3/18/2013
Authors: Dean C Ripple, Michael J Carrier, Richard E Cavicchi, Christopher B Montgomery, Zhishang Hu
Abstract: A common degradation pathway for protein-based drugs is the growth of protein aggregates or particles. Counting and characterization of these particles is needed to assure the quality, efficacy, and safety of this type of drug. The unusual physical ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913322

18. Modification of tethered bilayers by phospholipid exchange with vesicles
Topic: Drugs/Pharmaceuticals
Published: 2/27/2013
Authors: David J Vanderah, Rima Budvytyte, Mindaugas Mickevicius, Gintaras Valincius, Frank Heinrich
Abstract: Phosphatidylcholine and cholesterol exchange between vesicles and planar tethered bilayer lipid membranes (tBLMs) was demonstrated from electrochemical impedance spectroscopy (EIS), fluorescence microscopy (FM), and neutron reflectometry (NR) data. ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912490

19. Breast Cancer Biomarker Measurements and Standards
Topic: Drugs/Pharmaceuticals
Published: 1/24/2013
Authors: Kenneth D Cole, Lili Wang, Hua-Jun He
Abstract: Cancer is a heterogeneous disease characterized by changes in the levels and activities of important cellular proteins, including oncogenes and tumor suppressors. Genetic mutations cause changes in protein activity and protein expression levels that ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912867

20. NIST/NIH Vitamin D Metabolites Quality Assurance Program Report of Participant Results: Summer 2011 Exercise (Exercise 4)
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7893
Topic: Drugs/Pharmaceuticals
Published: 12/21/2012
Authors: Katrice A Lippa, Mary Bedner, Susan Shu Cheng Tai
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911154



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