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Topic Area: Drugs/Pharmaceuticals

Displaying records 11 to 20 of 33 records.
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11. Predictive Gold Nanocluster Formation Controlled by Metal-Ligand Complexes
Topic: Drugs/Pharmaceuticals
Published: 1/9/2012
Authors: John M. Pettibone, Jeffrey W Hudgens
Abstract: The formation of ligand-protected transition metal nanoclusters in size-selective syntheses is driven by the inherent properties of the protecting ligands. We have previously reported the selective, monodisperse product formation of phosphine protect ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908225

12. A Streamlined Hydrolysis Procedure for the LC/MS/MS Analysis of Cocaine in Wastewater Samples
Topic: Drugs/Pharmaceuticals
Published: 1/2/2012
Authors: Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We report a streamlined procedure for the routine analysis of cocaine in municipal wastewater. By adding NaOH (to 0.025 M) and incubating wastewater samples at 55 °C for two hours, cocaine and its principal metabolites are quantitatively converted i ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903657

13. A Comprehensive LC/MS/MS Method for the Determination of Cocaine and Other Drugs of Abuse in Municipal Wastewater: I. Quantification via SPE and Direct Injection
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Katrice A Lippa, Michele M Schantz, A. Lynn Roberts, Kevin Bisceglia
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903656

14. Quantification of Drugs of Abuse in Municipal Wastewater via SPE and Direct Injection Liquid Chromatography Mass Spectrometry
Topic: Drugs/Pharmaceuticals
Published: 9/24/2010
Authors: Michele M Schantz, Katrice A Lippa, Kevin Bisceglia, A. Lynn Roberts
Abstract: We present an isotopic dilution direct injection reverse phase liquid chromatography-tandem mass spectrometry (RPLC/MS/MS) method for the simultaneous determination of 23 drugs of abuse, drug metabolites, and human use markers in municipal wastewater ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904046

15. Fluorinated Copolymer Nanoparticles for Multimodal Imaging Applications
Topic: Drugs/Pharmaceuticals
Published: 2/18/2010
Authors: Mark M. Bailey, Christine M. Mahoney, Elodie Dempah, Jeffrey M Davis, Matthew Becker, Supang Khondee, Eric J. Munson, Cory J. Berkland
Abstract: Nanomaterials have emerged as valuable tools in biomedical imaging techniques, such as magnetic resonance imaging (MRI), fluorescence, positron emission tomography (PET), and others. Some have been designed to serve as multimodal imaging agents, com ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=902813

16. Isolation, Purification, and Full NMR Assignments of cyclopamine from Veratrum californicum
Topic: Drugs/Pharmaceuticals
Published: 6/24/2009
Authors: Daniel W Bearden, John E. Oatis, Pam Brunsfeld, James W. Rushing, Peter D. Moeller, Thomas N. Gallien, George W. Cooper
Abstract: The Hedgehog (Hh) signaling pathway is essential for embryogenesis and tissue homeostasis in the adult. However, it may also induce malignancies in a number of tissues when constitutively activated, and it also may have a role in other forms of nor ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832291

17. Study of interaction of the cyclin-dependent kinase 5 with its activator, p25 and with the p25-derived inhibitor, CIP
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7552
Topic: Drugs/Pharmaceuticals
Published: 1/15/2009
Authors: Antonio Cardone, Ram D Sriram, Wayne Albers, Harish C. Pant
Abstract: A high-affinity inhibitor protein called CIP, which can be produced by small truncations of p35, was earlier identified by Amin, Albers, and Pant. P35 is one of the physiological activators of cdk5, a member of the cyclin-dependent kinase family. The ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901184

18. Solid State Chemistry of Proteins: II. The Correlation of Storage Stability of Freeze-Dried Human Growth Hormone (hGH) With Structure and Dynamics in the Glassy Solid
Topic: Drugs/Pharmaceuticals
Published: 12/1/2008
Authors: Michael Pikal, Daniel Rigsbee, Michael L Roy, Dawn Galreath, Karl J Kovach, Bingquan S. Wang, John F Carpenter, Marcus T Cicerone
Abstract: This research presents storage stability of human growth hormone, hGH, in a variety of lyophilized formulations, including systems of varying sugar:hGH weight ratios for both sucrose and trehalose. Stability was assessed at multiple time points durin ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=852769

19. Cold Chain Storage of Vaccines: A Brief Introduction to Thermometry
Series: NIST Interagency/Internal Report (NISTIR)
Topic: Drugs/Pharmaceuticals
Published: 9/1/2008
Author: Dean C Ripple
Abstract: To maintain the efficacy of vaccines requires maintaining the storage temperature within well-defined limits; vaccine failure due to improper storage results in large direct and indirect public health costs. In this presentation, I give a brief intro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832372

20. Quantitation of HER2 and Telomerase Biomarkers in Solid Tumors with IgY Antibodies and Nanocrystal Detection
Topic: Drugs/Pharmaceuticals
Published: 5/15/2008
Authors: Yan Xiao, X Gao, G Gannot, M Emmert-Buck, S Srivastava, Paul D Wagner, Michael D. Amos, Peter E. Dr. Barker
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901234