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Topic Area: Biological Physics

Displaying records 1 to 10 of 17 records.
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1. Total free energy governs cell morphology ‹ A possible solution to obtain intrinsic cell modulus
Topic: Biological Physics
Published: 9/26/2013
Authors: Martin Y Chiang, Yanzi Yangben , Nancy J Lin, Li Yang
Abstract: Cells adjust their morphology in response to physical and chemical interactions with their environment. In this report, we deem that the fundamental nature of free energies associated with cell/substrate interactions regulates adherent cell morpholog ...

2. Immobilization of Proteins on Carboxylic Acid-Functionalized Nanopatterns
Topic: Biological Physics
Published: 11/28/2012
Authors: John Peter Ngunjiri, Daniel Joshua Stark, Tian Tian, Kimberly A Briggman, Jayne C Garno
Abstract: The immobilization of proteins on nanopatterned surfaces was investigated using in situ atomic force microscopy (AFM) and ex situ infrared reflectance-absorption spectroscopy (IRAS). The AFM-based lithography technique of nanografting provided contro ...

3. Out-of-plane Stokes imaging polarimeter for early skin cancer diagnosis
Topic: Biological Physics
Published: 7/1/2012
Authors: P. Ghassemi, Paul Lemaillet, Thomas Avery Germer, J. W. Shupp, S. Venna, M. E. Boisvert, K. E. Flanagan, M. H. Jordan, J. C. Ramella-Roman
Abstract: Optimal treatment of skin cancer before it metastasizes depends critically on early diagnosis and treatment. Imaging spectroscopy and polarized remittance have been utilized in the past for diagnostic purposes, but valuable information can be also o ...

4. Pronounced micro-segregation in a sorbitol water mixture observed through variable temperature neutron scattering
Topic: Biological Physics
Published: 5/16/2012
Authors: Shin G. Chou, Sheila Khodadadi, Joseph Curtis, Susan T Krueger, Evgenyi Shalaev, Alan Soper, Andy Fitch, T Narayanan, Michael Szutucki, Marcus T Cicerone
Abstract: In this study, we use small and wide angle X-ray and neutron scattering measurements, to study the structure of concentrated sorbitol solutions and glasses at different temperatures. The analysis of the data suggests the water forms clusters with a ...

5. Tetracysteine-Based Fluorescent Tags to Study Protein Localization and Trafficking in Plasmodium falciparum-Infected Erythrocytes
Topic: Biological Physics
Published: 8/10/2011
Authors: Georgeta Crivat, Fuyuki Tokumasu, Juliana Martha Sa , Thomas E. Wellems, Jeeseong Hwang
Abstract: Plasmodium falciparum (Pf) malaria parasites remodel host erythrocytes by placing membranous structures in the host cell cytoplasm and inserting proteins into the surrounding erythrocyte membranes. Dynamic imaging techniques with high spatial and tem ...

6. Generation and Mixing of Subfemtoliter Aqueous Droplets on Demand
Topic: Biological Physics
Published: 8/27/2009
Authors: Kristian Helmerson, Jianyong NMN Tang, Ana Jofre, Rani Kishore, Joseph Earl Reiner, Mark E Greene, Geoffrey M Lowman, John Denker, Christina NMN Willis, Lori Goldner
Abstract: We describe a novel method of generating monodisperse sub-femtoliter aqueous droplets on demand by means of piezoelectric injection. Droplets with volumes down to 200 aL are generated by this technique. The droplets are injected into a low refractive ...

7. Quantitative Characterization of Quantum Dot-labeled Lambda Phage for Escherichia coli Detection
Topic: Biological Physics
Published: 7/24/2009
Authors: Peter Yim, Matthew Lawrence Clarke, Michael McKinstry, Silvia Helena De Paoli Lacerda, Leonard F. Pease III, Marina A. Dobrovolskaia, Hyeong G. Kang, David Thomas Read, Shanmuga Sozhamannan, Jeeseong Hwang
Abstract: We rapidly and quantitatively detect biological pathogens by combining the specificity of bacteriophage lambda with the sensitivity of CdSe/ZnS quantum dot (QD)-based fluorescence. Specifically, QD-decorated lambda phages bind to and allow detection ...

8. Direct Measurement of Association and Dissociation Rates of DNA Binding in Live Cells by Fluorescence Correlation Spectroscopy
Topic: Biological Physics
Published: 7/1/2009
Authors: Ariel Michelman-Ribeiro, Davide Mazza, Tilman Rosales, Timothy J. Stasevich, Boukari Hacene, Vikas Rishi, Charles Vinson, Jay R. Knutson, James G. NcNally
Abstract: Measurement of live-cell binding interactions is vital for understanding the biochemical reactions that drive cellular processes. Here we develop, characterize and apply a new procedure to extract information about binding to an immobile substra ...

9. Dipolar Chains formed by synthesized cobalt nanocubes
Topic: Biological Physics
Published: 5/11/2009
Authors: Guangjun Cheng, Robert D Shull, Angela R Hight Walker
Abstract: Cobalt nanocubes with an average edge length of 50 nm and the epsilon crystalline structure were synthesized via thermo-decomposition in 1,2-dichlorobenzene at 120 oC in the presence of the surfactants. These nanocubes form dipolar chains upon drying ...

10. Conformational Effects on Excitonic Interactions in a Prototypical H-bonded Bichromophore: Bis(2-hydroxyphenyl)methane
Topic: Biological Physics
Published: 4/30/2009
Authors: David F Plusquellic, Nathan Pillsbury, Christian Mueller, Timothy Zwier
Abstract: Laser induced fluorescence (LIF), single vibronic level fluorescence, UV holeburning, and fluorescence-dip infrared (FDIR) spectroscopy have been carried out on bis-(2-hydroxyphenyl)methane (2HDPM) in order to characterize the ground and first excite ...

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