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You searched on: Topic Area: Bioscience Health Sorted by: date

Displaying records 31 to 40 of 274 records.
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31. CPTAC Studies 1 and 5: dissecting variability in multi-site LC-MS/MS proteomics through quality metrics and robust hierarchical multivariate statistics
Topic: Bioscience & Health
Published: 2/4/2014
Authors: Stephen E Stein, David M Bunk, Xia Wang, Matthew Chambers, Lorenzo J Vega-Montoto, David L. Tabb
Abstract: Shotgun proteomics experiments integrate a complex sequence of processes, any of which can introduce variability. Quality metrics computed from LC-MS/MS data have relied upon identifying MS/MS scans, but a new mode for the QuaMeter software produces ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914875

32. Influence of tissue, age, and environmental quality on global levels of genomic methylation in the American alligator (Alligator mississippiensis)
Topic: Bioscience & Health
Published: 1/7/2014
Authors: Benjamin B Parrott, John A Bowden, Satomi Kohno, Jessica A Cloy-McCoy, Jacqueline T Bangma, Thomas R Rainwater, Phillip M Wilkinson, John R Kucklick, Louis J Guillette
Abstract: Epigenetic modifications are key mediators of the interactions between the environment and an organism‰s genome. DNA methylation represents the best-studied epigenetic modification to date and is known to play key roles in regulating transcriptional ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914564

33. Tunable electrical conductivity in metal-organic framework thin film devices
Topic: Bioscience & Health
Published: 1/3/2014
Authors: Albert A. Talin, Andrea Centrone, Alexandra C. Ford, Michael E Foster, Vitalie Stavila, Paul M Haney, Robert Adam Kinney, Veronika A Szalai, Farid El Gabaly, Heayoung Yoon, Francois Leonard, Mark Allendorf
Abstract: We report a strategy for realizing tunable electrical conductivity in MOFs in which the nanopores are infiltrated with redox-active, conjugated guest molecules. This approach is demonstrated using thin-film devices of the MOF Cu3(BTC)2 (also known as ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913452

34. Reconstitution of cholesterol-dependent vaginolysin into tethered phospholipid bilayers: implications for bioanalysis
Topic: Bioscience & Health
Published: 12/13/2013
Author: David J. Vanderah
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914306

35. Airbrushed Nanofiber Scaffolds Support Bone Marrow Stromal Cell Differentiation
Topic: Bioscience & Health
Published: 11/1/2013
Authors: Carl George Simon Jr., Wojtek J Tutak, Sumona Sarkar, Tanya M. Farooque, Jyotsnendu J. Giri, Dongbo Wang, Sheng Lin-Gibson, Joachim Kohn, Durgadas Bolikal
Abstract: Nanofiber scaffolds are effective for tissue engineering since they emulate the fibrous nanostructure of native extracellular matrix (ECM). Although electrospinning has been the most common approach for fabricating nanofiber scaffolds, airbrushi ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912293

36. Determining carbapenemase activity with 18O labeling and targeted mass spectrometry
Topic: Bioscience & Health
Published: 10/16/2013
Authors: Meiyao Wang, Yang Shen, Illarion V Turko, Daniel Nelson, Shuwei Li
Abstract: Carbapenems are broad spectrum antibiotics considered as last resort drugs to treat bacterial infections. Carbapenem-hydrolyzing β-lactamases (also called carbapenemases), however, can confer bacterial resistance and represent a serious health t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914525

37. Comprehensive analysis of protein digestion using six trypsins reveals the origin of trypsin as a significant source of variability in proteomics
Topic: Bioscience & Health
Published: 10/11/2013
Authors: Stephen E Stein, Paul A Rudnick, Scott J Walmsley, Qian Dong, Alexey I Nesvizhskii, Yuxue Liang
Abstract: Trypsin is an endoprotease commonly used for sample preparation in proteomics experiments. Importantly, protein digestion is dependent on multiple factors, including the trypsin origin and digestion conditions. In-depth characterization of tryp ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=914042

38. TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses
Topic: Bioscience & Health
Published: 9/12/2013
Authors: John P Marino, Katharine Therese Briggs, Heather Cohen, Katya Ravid, Simon C. Robson, David M. Mosser
Abstract: Sepsis is a highly fatal disease caused by an initial hyperinflammatory response followed by a state of profound immunosuppression. Although it is well appreciated that the initial production of proinflammatory cytokines by macrophages accompanies th ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912870

39. Functionalization-Dependent Induction of Cellular Survival Pathways by CdSe Quantum Dots in Primary Normal Human Bronchial Epithelial Cells
Topic: Bioscience & Health
Published: 9/5/2013
Authors: Amber Nagy, Jennifer A Hollingsworth, Bin Hu, Andrea Steinbruck, Peter C. Stark, Cristina Rios Valdez, Momchilo Vuyisich, Michael H. Stewart, Donald H Atha, Bryant C Nelson, Rashi Iyer
Abstract: Quantum dots (QDs) are semiconductor nanocrystals exhibiting unique optical properties which can be exploited for many practical applications ranging from photovoltaics to biomedical imaging and drug delivery. They are increasingly manufactured in la ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=911778

40. Standard Practice for Determining the Relative Spectral Correction Factors for the Emission Signal of Fluorescence Spectrometers
Series: NIST Interagency/Internal Report (NISTIR)
Report Number: 7915
Topic: Bioscience & Health
Published: 8/15/2013
Author: Paul C DeRose
Abstract: This standard practice is intended to aid in the calibration and qualification of fluorescence spectrometers as part of complying with regulatory and other QA/QC requirements. It specifies the materials and procedures used in three different meth ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913001



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