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You searched on: Topic Area: Bioscience Health

Displaying records 381 to 390 of 470 records.
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381. Measurement of 8-Hydroxy-2'-Deoxyguanosine in DNA by High-Performance Liquid Chromatography-Mass Spectrometry: Comparison with Measurement by Gas Chromatography-Mass Spectrometry
Topic: Bioscience & Health
Published: 2/1/2001
Authors: M. Dizdaroglu, Pawel Jaruga, H Rodriguez
Abstract: Measurement of 8-hydroxy-2'-deoxyguanosine (8-OH-dGuo) in DNA by high-performance liquid chromatography/mass spectrometry (HPLC/MS) was studied. A methodology was developed for separation by LC of 8-OH-dGuo from intact and modified nucleosides i ...

382. Gene Expression Analysis on Medium-Density Oligonucleotide Arrays
Topic: Bioscience & Health
Published: 1/1/2001
Authors: R. Sinibaldi, C D O'Connell, H Rodriguez, C. Seidel
Abstract: As the human genome project continues toward its goal of sequencing the entire human genome by the end of 2003, this is providing unique opportunities for studying genetic variation in humans and its relationship with disease risk and aging. Consequ ...

383. Testing for the Antiphospholipid Syndrome: Importance of IgA Anti-beta 2-glycoprotein I
Topic: Bioscience & Health
Published: 12/17/2000
Authors: T.P. Greco, Michael D. Amos, A.M. Conti-Kelly, J.D. Naranjo, J.W. Ijdo

384. Enhanced Capacity for Electrophoretic Capture of Plasmid DNA by Agarase Treatment of Agarose Gels
Topic: Bioscience & Health
Published: 12/1/2000
Authors: Kenneth D Cole, B. Akerman
Abstract: Agarase was used investigate the effect of increasing the number of polymer ends on the electrophoretic trapping of circular DNA in agarose gels. The electric field strength required to trap circular DNA was found to be the same in control and treat ...

385. Laboratory Database to Manage Electrophoresis and Chromatography Separations and the Associated Samples
Topic: Bioscience & Health
Published: 12/1/2000
Author: Kenneth D Cole
Abstract: A database was developed to store, organize, and retrieve the data associated with electrophoresis and chromatography separations. It allows laboratories to store extensive data on saparation techniques (analytical and preparative). The data for gel ...

386. Repair of oxidative DNA damage in Drosophila melanogaster: identification and characterization of dOgg1, a second DNA glycosylase activity for 8-hydroxyguanine and formamidopyrimidines
Topic: Bioscience & Health
Published: 12/1/2000
Authors: C. Dherin, M. Dizdaroglu, H. Doerflinger, S. Boiteux, J. P. Radicella
Abstract: In Drosophila, the S3 ribosomal protein has been shown to act as a DNA glycosylase/AP lyase capable of releasing 8-hydroxyguanine (8-OH-Gua) in damaged DNA. Here we describe a second Drosophila protein (dOggl) with 8-OH-Gua and abasic (AP) site DNA ...

387. Infrared Spectroscopic Ellipsometry of Self-Assembled Monolayers
Topic: Bioscience & Health
Published: 11/28/2000
Author: Curtis W Meuse
Abstract: Ellipsometry measures the relative intensity of and the phase difference between the parallel (p) and perpendicular (s) components of an electric field vector interacting with a sample. In this paper, a technique using polarized Fourier transform in ...

388. Atomic force microscope imaging of molecular aggregation during self-assembled monolayer growth
Topic: Bioscience & Health
Published: 11/1/2000
Authors: I. Doudevski, W. A. Hayes, John Taylor Woodward IV, D. K. Schwartz

389. Characterization of a Novel 8-Oxoguanine-DNA Glycosylase Activity in Escherichia Coli and Identification of the Enzyme as Endonuclease VIII
Topic: Bioscience & Health
Published: 9/1/2000
Authors: T. K. Hazra, T. Izumi, R Venkataraman, Y W Kow, M. Dizdaroglu, Somenath Mitra
Abstract: 8-oxoguanine (G*), induced by reactive oxygen species, is mutagenic because it mispairs with A. The major G*-DNA glycosylase (OGG), namely, OGG1 in eukaryotes, or MutM in Escherichia coli, excises G* when paired in DNA with C, G and T, but not A, pr ...

390. Oxidative DNA Damage and Its Potential Use for Monitoring Oxidative Stress
Topic: Bioscience & Health
Published: 9/1/2000
Author: M. Dizdaroglu

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