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You searched on: Topic Area: Nanobiotechnology

Displaying records 11 to 20 of 31 records.
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11. Surface-Engineered Nanomaterials as X-ray Absorbing Adjuvant Agents for Auger-Mediated Chemo-Radiation
Topic: Nanobiotechnology
Published: 4/30/2013
Authors: Robert Francis Cook, Sang-Min Lee, De-Hao D. Tsai, Vincent A Hackley, Martin W. Brechbiel
Abstract: We demonstrate a prototype approach to formulate gold nanoparticle (AuNP)‹based X‹ray absorbing adjuvant agents through surface‹engineering of cisplatin pharmacophore (PtII) with lipoic acid‹modified polyacrylate (denoted as PtII‹AuNPs). Design of Pt ...

12. Temperature sculpting in yoctoliter volumes
Topic: Nanobiotechnology
Published: 2/14/2013
Authors: Joseph E Reiner, Joseph William Robertson, Daniel L Burden, Lisa K Burden, Arvind Kumar Balijepalli, John J Kasianowicz
Abstract: The ability to perturb large ensembles of molecules from equilibrium led to major advances in understanding reaction mechanisms in chemistry and biology. Here, we demonstrate the ability to control, measure, and make use of rapid temperature changes ...

13. Quantifying Dithiothreitol Displacement of Functional Ligands from Gold Nanoparticles
Topic: Nanobiotechnology
Published: 10/27/2012
Authors: De-Hao D. Tsai, Frank W DelRio, Sherrie R. Elzey, Suvajyoti S. Guha, Michael Russel Zachariah, Vincent A Hackley, Melanie P Shelton
Abstract: Dithiothreitol (DTT)-based displacement is widely utilized for separating ligands from their gold nanoparticle (AuNP) conjugates, a critical step for differentiating and quantifying surface-bound functional ligands and therefore the effective surface ...

14. Disentangling the effects of polymer coatings on silver nanoparticle agglomeration, dissolution, and toxicity to determine mechanisms of nanotoxicity
Topic: Nanobiotechnology
Published: 9/1/2012
Authors: Justin M Zook, Melissa Danielle Halter, Danielle Cleveland, Stephen E Long
Abstract: Silver nanoparticles (AgNPs) are frequently coated by a variety of polymers, which may affect various intertwined mechanisms of toxicity, including agglomeration and dissolution rate. Here, we measure how citrate, dextran, poly(ethylene glycol) (PEG ...

15. Tumor Necrosis Factor Interaction with Gold Nanoparticles
Topic: Nanobiotechnology
Published: 3/14/2012
Authors: De-Hao D. Tsai, Sherrie R. Elzey, Frank W DelRio, Robert I. MacCuspie, Suvajyoti S. Guha, Michael Russel Zachariah, Athena M Keene, Jeffrey D Clogston, Vincent A Hackley
Abstract: We report on a systematic investigation of molecular conjugation of tumor necrosis factor protein-α (TNF) onto gold nanoparticles (AuNPs) and the subsequent binding behavior to its antibody (anti-TNF). We employ a combination of physical and spe ...

16. Through-focus Scanning Optical Microscopy
Topic: Nanobiotechnology
Published: 12/31/2011
Author: Ravikiran Attota
Abstract: Through-focus scanning optical microscopy (TSOM) method provides three-dimensional information (i.e. the size, shape and location) about micro- and nanometer-scale structures. TSOM, based on a conventional optical microscope, achieves this by acquiri ...

17. Nanometrology Using Through-Focus Scanning Optical Microscopy Method
Topic: Nanobiotechnology
Published: 12/21/2011
Authors: Ravikiran Attota, Richard M Silver
Abstract: We present an initial review of a novel through-focus scanning optical microscopy (TSOM) imaging method that produces nanometer dimensional measurement sensitivity using a conventional bright-field optical microscope. In the TSOM method a target is ...

18. TSOM Method for Nanoelectronics Dimensional Metrology
Topic: Nanobiotechnology
Published: 11/18/2011
Author: Ravikiran Attota
Abstract: Through-focus scanning optical microscopy (TSOM) is a relatively new method that transforms conventional optical microscopes into truly three-dimensional metrology tools for nanoscale to microscale dimensional analysis. TSOM achieves this by acquirin ...

19. SEM Induced Shrinking of Solid State Nanopores for Single Molecule Detection
Topic: Nanobiotechnology
Published: 9/22/2011
Authors: Anmiv Prahbu, Kevin J Freedman, Joseph William Robertson, Zhorro Nikolov, John J Kasianowicz, MinJun Kim
Abstract: We have investigated the shrinkage of solid state nanopores by a scanning electron microscope and find the process to be reproducible and dependant beam parameters such as the accelerating voltage and electron flux. The shrinking phenomenon does ...

20. O2 A-band line parameters to support atmospheric remote sensing. Part II: The rare isotopologues
Topic: Nanobiotechnology
Published: 7/21/2011
Authors: Joseph Terence Hodges, David A Long, Daniel K Havey, S. S. Yu, M Okumura, Charles E Miller
Abstract: Frequency-stabilized cavity ring-down spectroscopy (FS-CRDS) was employed to measure over 100 transitions in the R-branch of the b1Σg+←X3Σg-(0,0) band for the rare O2 isotopologues. The use of 17O- and 18O-enriched mixtures allowed fo ...

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