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Topic Area: Biomaterials

Displaying records 61 to 70 of 94 records.
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61. Osteoblast Response to Protein Adsorption to 3D Polymer Scaffolds Through Pre-Ageing in Cell Medium
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr, Kaushik Chatterjee, Stevephen Hung
Abstract: Protein adsorption mediates biological responses to materials. When a biodegradable polymer scaffold is placed in aqueous, physiological medium, proteins adsorb onto the scaffold surface. The total amount, composition and structure of the adsorbed pr ...

62. Modulus-Driven Differentiation of Marrow Stromal Cells in 3D Is Independent of Cytoskeletal Integrity
Topic: Biomaterials
Published: 4/11/2011
Authors: Carl George Simon Jr, Kaushik Chatterjee, Sapun Parekh, Sheng Lin-Gibson, Nicole M. Moore, Marcus T Cicerone, Marian F Young
Abstract: Cell functions such as proliferation, migration, and differentiation are key physiological processes that are influenced by the physiochemical extracellular environment. We report on the effect of three-dimensional (3D) scaffold modulus on human bon ...

63. Effect of 3D Hydrogel Scaffold Stiffness on Human Bone Marrow Stromal Cell Differentiation
Topic: Biomaterials
Published: 11/1/2010
Authors: Carl George Simon Jr, Sapun Parekh, Marcus T Cicerone, Sheng Lin-Gibson, Kaushik Chatterjee, Marian F Young
Abstract: There is growing recognition cells can sense and respond to the mechanical properties of tissue scaffolds and that these interactions are critical in optimizing scaffold design [1-4]. Previous studies in planar 2D culture format have shown that human ...

64. Fine-tuning of polymeric resins and their interfaces with amorphous calcium phosphate. A strategy for designing effective remineralizing dental composites
Topic: Biomaterials
Published: 9/29/2010
Authors: Joseph M Antonucci, Drago Skrtic
Abstract: For over a decade our group has been designing, preparing and evaluating bioactive, remineralizing composites based on amorphous calcium phosphate (ACP) fillers embedded in polymerized methacrylate resin matrices. In these studies a major focus has b ...

65. Effect of 3D Hydogel Scaffold Modulus and Topology on Human Bone Marrow Stromal Cell Fate
Topic: Biomaterials
Published: 9/1/2010
Authors: Kaushik Chatterjee, Sheng Lin-Gibson, Sapun Parekh, Nicole M. Moore, Marcus T Cicerone, marian f young, Carl George Simon Jr
Abstract: There is growing recognition that cells can sense and respond to the physical cues from their environment, such as stiffness, mechanical loading and topology. Physical properties of the matrix can direct cellular response and are critical in the desi ...

66. Diffusion of Ions between Two Solutions Saturated With Respect to Hydroxyapatite: A Mechanism for Subsurface Demineralization of Teeth
Series: Journal of Research (NIST JRES)
Topic: Biomaterials
Published: 7/17/2010
Author: Laurence Chung Lung Chow
Abstract: Diffusion-controlled dissolution and precipitation reactions occur in many biological systems and some non-stirred in vitro systems. Previous studies have shown that differences in the diffusion rates of ions involved in a dissolution/precipitation ...

67. Combinatorial Screening of Hydrogels for 3-D Cell Culture: Osteoblasts in Stiffness Gradients Yield Graded Tissues
Topic: Biomaterials
Published: 7/1/2010
Authors: Kaushik Chatterjee, Sheng Lin-Gibson, William E Wallace III, Marian F Young, Carl George Simon Jr
Abstract: A combinatorial library approach was used to demonstrate that hydrogel scaffold modulus can enhance osteoblast differentiation driving formation of a 3-D graded tissue construct. Though many previous studies have focused on screening cell-material i ...

68. Preparation and Properties of Nanoparticles of Calcium Phosphates with Various Ca/P Ratios
Topic: Biomaterials
Published: 7/1/2010
Authors: Limin Sun, Laurence Chung Lung Chow, Stanislav A. Frukhtbeyn, John E Bonevich
Abstract: This study aimed at preparing and studying the properties of nanoparticles of calcium phosphate (nCaP) with Ca/P ratios ranging from 1.0 to 1.67 using a spray-drying technique. Micro-structural analyses results suggested that the nCaPs with Ca/P ra ...

69. Tooth chipping can reveal bite forces and diets of fossil hominins
Topic: Biomaterials
Published: 6/16/2010
Authors: Paul Constantino, James J. Lee, H Chai, Bernhard Zipfel, Charles Ziscovici, Brian Ronald Lawn, Peter Lucas
Abstract: Fossil hominin tooth enamel often exhibits antemortem edge chipping (Robinson 1954; Tobias 1967; Wallace 1973). Here we apply a simple fracture equation to estimate peak bite forces from the sizes of such chips. This equation, previously validated ...

Topic: Biomaterials
Published: 6/14/2010
Authors: H Chai, James J. Lee, Brian Ronald Lawn
Abstract: We present definitive evidence for crack growth from internal defects called 'tufts' in human enamel. Side walls of slices sawn from extracted human teeth are observed during loading to 'failure'. 'Longitudinal' and 'transverse' slices (parallel ...

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