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Topic Area: Biomaterials

Displaying records 51 to 60 of 94 records.
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51. Osteoblast Response to Serum Protein Adsorption in 3D Polymer Scaffolds
Topic: Biomaterials
Published: 5/1/2012
Authors: Carl George Simon Jr, Girish Kumar, Kaushik Chatterjee, Stevephen Hung
Abstract: Protein adsorption is known to direct biological response to biomaterials and is important in determining cellular response in tissue scaffolds. In this study we investigated the effect of adsorbed serum proteins on cell attachment and proliferation ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=909572

52. Nano-Apatitic Composite Scaffolds for Stem Cell Delivery and Bone Tissue Engineering
Topic: Biomaterials
Published: 4/15/2012
Authors: Hockin H. K. Xu, Carl George Simon Jr
Abstract: The need for bone defect repair and regeneration arises from trauma, disease, congenital deformity, and tumor resection. Bone fracture occurs to seven million people each year in the United States, and musculoskeletal conditions cost $215 billion ann ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904167

53. OOF3D: An Image-Based Finite Element Solver for Materials Science
Topic: Biomaterials
Published: 3/28/2012
Authors: Valerie R. Coffman, Andrew Charles edmu Reid, Stephen A Langer, Gunay Dogan
Abstract: Recent advances in experimental techniques (micro CT scans, automated serial sectioning, electron back-scatter diffraction, synchrotron radiation x-rays) have made it possible to characterize the full, three dimensional structure of real materials. S ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=905504

54. Freeform Fabricated Scaffolds with Roughened Struts that Enhance both Stem Cell Proliferation and Differentiation by Controlling Cell Shape
Topic: Biomaterials
Published: 3/1/2012
Authors: Girish Kumar, Carl George Simon Jr, Michael S. (Michael Stephan) Waters, Tanya M. Farooque, Marian F Young
Abstract: We demonstrate that imparting freeform fabricated (FFF) scaffolds with surface roughness on their struts enhances osteogenic differentiation of primary human bone marrow stromal cells (hBMSCs) by controlling cell shape. Previous work showed that hBM ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=910664

55. Morphological Changes Driven by Nanofibrous Scaffolds Induce Marrow Stromal Cell Osteogenesis
Topic: Biomaterials
Published: 10/11/2011
Authors: Carl George Simon Jr, Kaushik Chatterjee, Christopher K. Tison, Girish Kumar, Patrick S Pine, Marc L Salit, Jennifer H McDaniel, Marian F Young
Abstract: Cells are sensitive to tissue scaffold architecture and these cell-material interactions drive cell functions critical in tissue regeneration. Results presented here demonstrate that nanofiber scaffolds force primary human bone marrow stromal cells ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908027

56. Hybrid Cell Adhesive Material for Instant Dielectrophoretic Cell Trapping and Long Term Cell Function Assessment
Topic: Biomaterials
Published: 8/16/2011
Authors: Darwin R Reyes-Hernandez, Jennifer S. Hong, John T Elliott, Michael Gaitan
Abstract: We present the development and evaluation of an engineered hybrid cell adhesive surface for instant dielectrophoretic trapping and patterning of cells in a microfluidic device. This work demonstrates that a hybrid cell adhesive material (hCAM) prepar ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=906647

57. Combinatorial Screening of Osteoblast Response to 3D Nano-Composite Tissue Scaffolds Using Gradients and Arrays
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr, Kaushik Chatterjee, Limin Sun, Laurence Chung Lung Chow, Marian F Young
Abstract: Current methods for combinatorial and high-throughput (CHT) screening of cell-material interactions utilize a two-dimensional (2D) format where cells are presented on flat materials surfaces [1]. However, cell response in 3D scaffolds is more represe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907330

58. Effect of 3D Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr, Girish Kumar, Marian F Young
Abstract: Structural properties of polymeric scaffolds for tissue engineering play a key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaff ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907329

59. NIST Reference Material Scaffolds Characterized for Cell Response
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr, Jeff M Coles
Abstract: Reference scaffolds characterized for cell response are being developed for use as a standard for biological characterization of new scaffolds. The need for reference scaffolds to serve as a calibration standard between labs has been identified as c ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907327

60. Nanofiber Scaffolds Induce Morphological Changes in hBMSCs Critical for Osteogenic Differentiation
Topic: Biomaterials
Published: 4/24/2011
Authors: Carl George Simon Jr, Girish Kumar, Christopher K. Tison
Abstract: Utilizing tissue scaffold architecture to induce stem cell differentiation is of tremendous importance to the regenerative medicine community. To this end, we have investigated the effect of nanofiber scaffold structure on primary human bone marrow s ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907328



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