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Author: Wyatt Vreeland

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1. Microfluidic-Enabled of Liposomes Elucidate Size-Dependent Transdermal Transport
Published: 3/21/2014
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Don L. DeVoe, Julia Finkel, Mariana Junqueira, Zenaide Quezado
Abstract: Microfluidic synthesis of small and nearly-monodisperse liposomes is used to investigate the size-dependent passive transdermal transport of nanoscale lipid vesicles. While large liposomes with diameters above 105 nm are found to be excluded from dee ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=915017

2. Microfluidic preparation of liposomes to determine particle size influence on cellular uptake mechanisms
Published: 10/3/2013
Authors: Wyatt N Vreeland, Abhay U Andar, Renee R Hood, Don L. DeVoe, Peter W Swaan
Abstract: Purpose: This study investigates the cellular uptake and trafficking of liposomes in Caco-2 cells, using vesicles with distinct average diameters ranging from 40 nm-276 nm. Liposomes were prepared by microfluidic hydrodynamic flow focusing, producing ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913538

3. Microfluidic Synthesis of Nano-Liposomal Anesthetics
Published: 5/12/2013
Authors: Wyatt N Vreeland, Renee R Hood, Eric Kendall, Mariana Junqueira, Julia Finkel, Don L. DeVoe
Abstract: Topical anesthesia has the ability to provide painless application of pain management medications for minor procedures such as venipuncture, particularly in the pediatric population. Liposomes have been proposed as a highly advantageous nanocarrier f ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=913770

4. A rapid, low-cost preparation of monodisperse niosomes in a microfluidic platform
Published: 6/1/2010
Authors: Catherine T. Lo, Andreas Jahn, Wyatt N Vreeland, Laurie E Locascio
Abstract: Niosomes are synthetic membrane vesicles made of self-assembled non-ionic surfactants (i.e. amphiphilic organic compounds). They bear the same properties as liposomes, namely having an aqueous interior that is separated from the exterior aqueous env ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904028

5. Effects of temperature, acyl chain length, and flow-rate ratio on liposome formation and size in a microfluidic hydrodyanmic focusing device
Published: 3/21/2010
Authors: Justin M Zook, Wyatt N Vreeland
Abstract: Microfluidic hydrodynamic focusing of an alcohol/lipid mixture into a narrow fluid stream by two oblique buffer streams provides a controlled and reproducible method of forming phospholipid bilayer vesicles (i.e., liposomes) with relatively monodispe ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903474

6. Magnetic connectors for microfluidic applications
Published: 1/1/2010
Authors: Francisco Javier Atencia, Gregory A Cooksey, Andreas Jahn, Justin M Zook, Wyatt N Vreeland, Laurie E Locascio
Abstract: We present a new type of connector based on a simple idea: using a ring magnet on one side of the microfluidic chip and a disc magnet on the other side to provide the interfacial force necessary to provide a sealed connection between tubing or needle ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903395

7. The Proceedings of {mu}TAS 2008 Conference
Published: 11/20/2008
Authors: Laurie E Locascio, Michael Gaitan, Brian M. Paegel, David J Ross, Wyatt N Vreeland
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901090

8. Unexpectedly High Entrapment Efficiency in Nanometer Scale Liposomes With Hydrodynamic Focusing Using Continuous-Flow Microfluidics
Published: 10/16/2008
Authors: Andreas Jahn, Joseph Earl Reiner, Wyatt N Vreeland, Don DeVoe, Laurie E Locascio, Michael Gaitan
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=33075

9. Contactless Differential Conductivity Detection
Published: 10/12/2008
Authors: Gordon Allan Shaw, David J Ross, Steven Earl Fick, Wyatt N Vreeland
Abstract: We propose a new technique, contactless differential conductivity detection (CDCD,) to improve the detection limit of contactless conductivity detection for capillary and microchannel electrophoresis. By exploiting a 3-electrode differential configu ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=824689

10. Microfluidic DNA Analysis Systems for Forensic Applications
Series: Special Publication (NIST SP)
Report Number: 1083
Published: 7/18/2008
Authors: Michael Gaitan, Jayna J Shah, Darwin R Reyes-Hernandez, Pierre-Alain Auroux, Jon C Geist, Laurie E Locascio, Wyatt N Vreeland, David J Ross, Peter M Vallone, Paul Smith, Nicole Morgan, Tom Pohida, John Kakareka, Annelise Barron
Abstract: This report summarizes the NIST effort on microfluidic DNA analysis systems for forensic applications sponsored by the National Institute of Justice. Currently emerging microfluidics-based forensic systems are implemented in silica (glass) because t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=33078



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