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Author: laurie locascio

Displaying records 21 to 30 of 98 records.
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21. Unexpectedly High Entrapment Efficiency in Nanometer Scale Liposomes With Hydrodynamic Focusing Using Continuous-Flow Microfluidics
Published: 10/16/2008
Authors: Andreas Jahn, Joseph E. (Joseph E.) Reiner, Wyatt N Vreeland, Don DeVoe, Laurie E Locascio, Michael Gaitan
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=33075

22. Development of Aptamer-Based Affinity Assays Using Temperature Gradient Focusing: Minimization of the Limit of Detection
Published: 8/1/2008
Authors: Matthew S Munson, John Meacham, David J Ross, Laurie E Locascio
Abstract: A method is described for an aptamer-based affinity assay using a combination of two non-conventional techniques, temperature gradient focusing (TGF) and field amplified continuous sample injection TGF (FACSI-TGF), with fluorescence detection. Human ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832288

23. Microfluidic DNA Analysis Systems for Forensic Applications
Series: Special Publication (NIST SP)
Report Number: 1083
Published: 7/18/2008
Authors: Michael Gaitan, Jayna J Shah, Darwin R Reyes-Hernandez, Pierre-Alain Auroux, Jon C Geist, Laurie E Locascio, Wyatt N Vreeland, David J Ross, Peter M Vallone, Paul Smith, Nicole Morgan, Tom Pohida, John Kakareka, Annelise Barron
Abstract: This report summarizes the NIST effort on microfluidic DNA analysis systems for forensic applications sponsored by the National Institute of Justice. Currently emerging microfluidics-based forensic systems are implemented in silica (glass) because t ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=33078

24. Controlled Encapsulation of a Hydrophilic Drug Simulant in Nano-Liposomes Using Continuous Flow Microfluidics
Published: 6/4/2008
Authors: Andreas Jahn, Joseph E. (Joseph E.) Reiner, Wyatt N Vreeland, Don DeVoe, Laurie E Locascio, Michael Gaitan
Abstract: A new method to tailor the size and size distribution of nanometer scale liposomes and control loading of liposomes with a model drug in a continuous-flow microfluidic design is presented. Size and size dispersion are determined with tandem Asymmetr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=32987

25. Liposome-Templated Supramolecular Assembly of Responsive Alginate Nanogels
Published: 3/14/2008
Authors: Jennifer S. Hong, Wyatt N Vreeland, Silvia H. De Paoli Lacerda, Laurie E Locascio, Michael Gaitan, Srinivasa R. Raghavan
Abstract: Nanosized gel particles (nanogels) are of interest for a variety of applications, including controlled release of drugs and single-molecule encapsulation. Here, we employ the cores of nanoscale liposomes as reaction vessels to template the assembly o ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=32779

26. Preparation of Nanoparticles by Continuous-Flow Microfluidics
Published: 2/15/2008
Authors: Andreas Jahn, Joseph E. (Joseph E.) Reiner, Wyatt N Vreeland, Don DeVoe, Laurie E Locascio, Michael Gaitan
Abstract: We review a variety of micro- and nanoparticle formulations produced with microfluidic methods. A diverse variety of approaches to generate micro-scale and nano-scale particles have been reported. Here we emphasize the use of microfluidics, specifica ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=32842

27. Cleavage of Peptides and Proteins Using Light-Generated Radicals from Titanium Dioxide
Published: 10/1/2007
Authors: David M Bunk, Barbara J. (Jo) Jones, Mathew J. Vergne, Laurie E Locascio, M A Hayes
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904240

28. Liposome Characterization with Fluorescence Cumulant Analysis
Published: 6/8/2007
Authors: Joseph E. (Joseph E.) Reiner, Andreas Jahn, Laurie E Locascio, Michael Gaitan, John J Kasianowicz
Abstract: Liposomes are self-assembled spherical vesicles comprised of a lipid bilayer membrane that segregates an internal aqueous environment from an external aqueous environment. These nanometer-scale structures have demonstrated potential for targeted drug ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=32666

29. Using Pattern Homogenization of Binary Masks to Fabricate Microfluidic Structures With 3D Topography
Published: 5/2/2007
Authors: Francisco Javier Atencia, Susan E. Barnes, Jack F Douglas, John Meacham, Laurie E Locascio
Abstract: Because fluids at the microscale form three dimensional interfaces and are subject to three dimensional forces, the ability to create microstructures with modulated topography over large areas could greatly improve control over microfluidic phenomena ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830553

30. Microfluidic Directed Formation of Liposomes of Controlled Size
Published: 4/24/2007
Authors: Andreas Jahn, Wyatt N Vreeland, Don DeVoe, Laurie E Locascio, Michael Gaitan
Abstract: A new method to tailor liposome size and size distribution in a microfluidic format is presented. Liposomes are spherical structures formed from lipid bilayers that are from tens of nanometers to several micrometers in diameter. Liposome size and siz ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=32578



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