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1. Investigations into the potential contribution of a thermal mechanism for pulsed-high intensity focused ultrasound mediated delivery
Brian E. O'Neill, Howard Vo, Mary Angstadt, Victor Frenkel, Bradford Wood, Timothy P Quinn
The mechanism behind pulsed high intensity focused ultrasound (pHIFU) effects leading to increased drug delivery are currently poorly understood. In this work, the thermal dose and peak temperatures associated with a typical pHIFU treatment were meas ...
2. A CONFINED COMPRESSION TECHNIQUE FOR HYDRAULIC CONDUCTIVITY MEASUREMENT IN SOFT TISSUES
Brian E. O'Neill, Timothy P Quinn, Victor Frenkel, King C. Li
A biphasic model of soft tissue has been combined with a simple confined compression test to measure the hydraulic conductivity of soft tissues. The biphasic model treated the tissue as a mixture of an incompressible fluid and porous elastic solid. ...
3. A Coupled Arc and Droplet Model of GMAW
Timothy P Quinn, M Szanto, T Gilad, I Shai
A model of gas metal arc welding was developed that solves the magneto-hydrodynamic equations for the flow and temperature fields of the molten electrode and the plasma simultaneously, to form a fully coupled model. A commercial finite element code ...
4. A Mathematical Model of Wire Feeding Mechanisms in GMAW
T M Padilla, D. R. Munoz, Timothy P Quinn, R. A. Rorrer
A Hertzian based contact model of the friction between the welding wire and the wire liner has been developed to predict the wire pulling force for gas metal arc welding (GMAW). The model predicts a 2.5:1exponential increase in wire pulling force as ...
5. A Multi-Phasic Continuum Damage Mechanics Model of Mechanically Induced Increased Permeability in Tissues
Brian O'Neill, Timothy P Quinn, Victor F. Frankel, King C. Li
Recently, we have reported enhanced permeability of tissues due to in vivo treatment with pulsed high intensity focused ultrasound (pHIFU). This new therapy has shown promise as a way of increasing the penetration of large drug molecules both out of ...
6. A Welding Cell That Supports Remote Collaboration
James D Gilsinn, William G Rippey, Joseph A Falco, Timothy P Quinn, Robert Russell, Keith A Stouffer
Discrete part manufacturers using robotic arc welding cells often have several more
geographically distributed plants than welding experts. This ratio often leads to costly downtimes
due to both logistic and communication deficiencies between weld ...
7. A Welding Cell With Its Own Web Site
Timothy P Quinn
Communications technology is allowing welding engineers to interact in the operation of a welding cell from a distance, as if they were physically present. The remote engineer can look at the weld, watch the robot motion, read front panel displays a ...
8. An Experimental Method for Measuring Mechanical Properties of Rat Pulmonary Arteries Verified With Latex
Journal of Research (NIST JRES)
Elizabeth S Drexler, Andrew J Slifka, J Wright, Christopher N McCowan, Dudley Finch, Timothy P Quinn, J D McCloskey, Dunbar Ivy, Robin Shandas
A study of the biomechanics and hemodynamics of pulmonary hypertension is incomplete without including mechanical properties data comparing healthy and diseased arterial tissue. In the initial stabe of this study, Sprague-Dawley rats will be induced ...
9. An instrumented bioreactor for mechanical stimulation and real-time, nondestructive evaluation of
engineered cartilage tissue
Jenni R. Popp, Justine Roberts, Douglas V Gallagher, Kristi S Anseth, Stephanie Bryant, Timothy P Quinn
Mechanical stimulation is essential for chondrocyte metabolism and cartilage matrix deposition. In
vitro, mechanical stimulation is accomplished via culture in a bioreactor. Traditional methods for
evaluating the developing tissue are destructive ...
10. Constitutive Models for a Poly(e-caprolactone) Scaffold
Timothy P Quinn, Tammy L. Oreskovic, Christopher N McCowan, N Washburn
We investigate material models for a porous, polymeric scaffold used for bone. The material was made by co-extruding poly (e-caprolactone) (PCL), a biodegradable polyester, and poly(ethylene oxide)(PEO). The water soluble PEO was removed resulting in ...