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Author: timothy quinn
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1. Effects of Processing on Microstructure and Mechanical Properties of Ti-6Al-4V Fabricated using Electron Beam Melting (EBM), Part 1: Distance from Build Plate and Part Size
Published: 6/20/2013
Authors: Nikolas Wilson Hrabe, Timothy P Quinn, Ryan Kircher
Abstract: Selective electron beam melting (EBM) is a layer-by-layer additive manufacturing technique that shows great promise for fabrication of medical devices and aerospace components. Before its potential can be fully realized, however, a deeper understand ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912252

2. Effects of Processing on Microstructure and Mechanical Properties of Ti-6Al-4V Fabricated using Electron Beam Melting (EBM), Part 2: Energy Input, Orientation, and Location
Published: 6/20/2013
Authors: Nikolas Wilson Hrabe, Timothy P Quinn, Ryan Kircher
Abstract: Selective electron beam melting (EBM) is a layer-by-layer additive manufacturing technique that shows great promise for fabrication of medical devices and aerospace components. Before its potential can be fully realized, however, a deeper understand ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=912253

3. An instrumented bioreactor for mechanical stimulation and real-time, nondestructive evaluation of engineered cartilage tissue
Published: 6/1/2012
Authors: Jenni R. Popp, Justine Roberts, Douglas V Gallagher, Kristi S Anseth, Stephanie Bryant, Timothy P Quinn
Abstract: Mechanical stimulation is essential for chondrocyte metabolism and cartilage matrix deposition. In vitro, mechanical stimulation is accomplished via culture in a bioreactor. Traditional methods for evaluating the developing tissue are destructive ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=909682

4. Tissue Engineered Scaffolds for Screening Nanoparticle - Cell Interactions
Published: 4/21/2010
Authors: Kavita M Jeerage, Elisabeth Mansfield, Tammy L. Oreskovic, Nikki Serene Rentz, Timothy P Quinn
Abstract: Long-term studies of nanoparticle-cell interactions require an advanced tissue-like environment in which nanoparticles are encapsulated with a population of cells for real-time and end-point analysis. By using soft tissue-mimicking hydrogels, the cel ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=904330

5. Evaluation of Polydimethylsiloxane Modification Methods for Cell Response
Published: 2/20/2009
Authors: Lisa Pakstis, Alan Zheng, Theodore Vincent Vorburger, Joy P Dunkers, Timothy P Quinn, Marcus T Cicerone
Abstract: Many methods exist in the literature to modify surfaces with extracellular matrix (ECM) proteins prior to cell attachment. However, there are few studies that systematically compare surface characterization and cell response results among different m ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=852760

6. Pulsed high intensity focused ultrasound mediated delivery: Mechanisms and efficacy in murine muscle
Published: 2/1/2009
Authors: Brian O'Neill, Howard Vo, Mary Angstadt, Timothy P Quinn, Victor Frenkel
Abstract: High intensity focused ultrasound (HIFU) is generally thought to interact with biological tissues in two ways: hyperthermia (heat) and acoustic cavitation. Pulsed mode HIFU has recently been demonstrated to increase the efficacy of a variety of drug ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=853629

7. Stiffening of the Extrapulmonary Arteries in Chronic Hypoxic Pulmonary Hypertension
Published: 7/1/2008
Authors: Elizabeth S Drexler, J. E. Bischoff, Christopher N McCowan, Andrew J Slifka, Timothy P Quinn, Robin Shandas, Dunbar Ivy, K. R. Stenmark
Abstract: It is increasingly appreciated that changes in the compliance properties of large blood vessels are critical determinants of ventricular afterload and ultimately dysfunction. Little is known of the mechanical properties of large vessels in the settin ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=50522

8. Investigations into the potential contribution of a thermal mechanism for pulsed-high intensity focused ultrasound mediated delivery
Published: 12/3/2007
Authors: Brian E. O'Neill, Howard Vo, Mary Angstadt, Victor Frenkel, Bradford Wood, Timothy P Quinn
Abstract: The mechanism behind pulsed high intensity focused ultrasound (pHIFU) effects leading to increased drug delivery are currently poorly understood. In this work, the thermal dose and peak temperatures associated with a typical pHIFU treatment were meas ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=50632

9. MATERIAL MODEL MEASUREMENTS AND PREDICTIONS FOR A RANDOM PORE POLY(Epsilon-CAPROLACTONE) SCAFFOLD
Published: 7/2/2007
Authors: Timothy P Quinn, Tammy L. Oreskovic, Forrest Andrew Landis, N. R. Washburn
Abstract: We investigate material models for a polymeric scaffold used for bone. The material was made by co-extruding poly(¿¿-caprolactone) (PCL), a biodegradable polyester, and poly(ethylene oxide) (PEO). The water soluble PEO was removed resulting in a poro ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=50206

10. A CONFINED COMPRESSION TECHNIQUE FOR HYDRAULIC CONDUCTIVITY MEASUREMENT IN SOFT TISSUES
Published: 6/29/2007
Authors: Brian E. O'Neill, Timothy P Quinn, Victor Frenkel, King C. Li
Abstract: A biphasic model of soft tissue has been combined with a simple confined compression test to measure the hydraulic conductivity of soft tissues. The biphasic model treated the tissue as a mixture of an incompressible fluid and porous elastic solid. ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=50495



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