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Author: john kasianowicz
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61. Molecular-scale Structural and Functional Characterization of Sparsely Tethered Bilayer Membranes
Duncan McGillivray, Gintaras Valincius, David J Vanderah, W Febo-Ayala, John Taylor Woodward IV, F Hienrich, John J Kasianowicz, M Losche
Surface-tethered biomimetic bilayer membranes (tethered lipid bilayer membranes, tBLMs) have been formed on gold surfaces from phospholipids and a synthetic 1-thiahexa(ethy lene oxide) lipid, WC14. They have been characterized using electrochemical i ...
62. Solution Analysis by Threading Single Molecules Through a Self-Assembled Nanometer-Scale Pore
John J Kasianowicz, S. E. Henrickson, B Robertson, H H. Weetall
We show here the principles for using a single nanometer-scale pore to detect a wide variety of analytes (e.g. small ions, proteins, antigens, antibodies, DNA sequences). The analyte recognition site or hapten is covalently attached to a linear poly ...
63. The Mitochondrial Apoptosis-Induced Channel MAC and Bax Channels Are Regulated by Cytochrome C
Li Guo, D Pietkiewicz, M M Pavlov, John J Kasianowicz, L M Dejean, S J Korsmeyer, B Antonsson, K W Kinnally
l-2 family proteins regulate the appearance of the high-conductance channel MAC (mitochondrial apoptosis-induced channel) 1 in the outer membranes of mitochondria early in apoptosis and regulate the release of cytochrome c during commitment to apopt ...