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Author: pawel jaruga
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1. A Comparative Study of Biomarkers of Oxidative DNA Damage Used to Detect Free Radical Damage in Tissue-Engineered Skin
Published: 1/1/2004
Authors: H Rodriguez, Pawel Jaruga, M Birincioglu, Peter E. Dr. Barker, C D O'Connell, M. Dizdaroglu
Abstract: The process of tissue engineering often involves the mixing of cells with polymers that may cause inflammation to the tissue and thus elevate the level of endogenous free radical production. In order to assure that such composite materials are free ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830345

2. A Major Role for Non-Enzymatic Antioxidant Processes in the Radioresistance of Halobacterium salinarum
Published: 4/1/2011
Authors: M Miral Dizdar, Pawel Jaruga, Courtney K Robinson, Kim Webb, Amardeep Kaur, Nitin S Baliga, Allen Place, Jocelyne DiRuggiero
Abstract: Oxidative stress occurs when the generation of reactive oxygen species (ROS) exceeds the capacity of the cell‰s endogenous systems to neutralize them. We analyzed the oxidative stress responses and cellular damage of the archaeon Halobacterium salina ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907681

3. Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice
Published: 2/1/2009
Authors: Guldal Kirkali, N de Souza-Pinto, Pawel Jaruga, V. Bohr, M Miral Dizdar
Abstract: Cockayne syndrome (CS) is a human genetic disorder characterized by sensitivity to UV radiation, neurodegeneration, premature aging among other phenotypes. CS complementary group B (CS-B) gene (csb) encodes the CSB protein (CSB) that is involved in b ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832387

4. Arabidopsis Thaliana Ogg1 Protein Excises 8-Hydroxyguanine and 2,6- Diamino-4-hydroxy-5-formamidopyrimidine from Oxidative Damaged DNA Containing Multiple Lesions
Published: 3/18/2003
Authors: T Morales-Ruiz, M Birincioglu, Pawel Jaruga, H Rodriguez, T. Roldan-Arjona, M Miral Dizdar
Abstract: A functional homologue of eukaryotic Ogg1 proteins in the model plant Arabidopsis thaliana has recently been cloned, isolated, and characterized [Garcia-Ortiz, M.V., Ariza, R.R., and Roldan-Arjona, T. (2001) Plant Mol. Biol. 47, 795-804]. This enzym ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830365

5. Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound
Published: 6/1/2006
Authors: D. C. Malins, K. M. Anderson, J. J. Stegeman, Pawel Jaruga, V. M. Green, N. K. Gilman, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908169

6. Biomarkers Used to Detect Genetic Damage in Tissue-Engineered Skin
Published: 1/1/2003
Authors: C D O'Connell, Peter E. Dr. Barker, M A Marino, P McAndrew, Donald H Atha, Pawel Jaruga, M Birincioglu, M. Dizdaroglu, H Rodriguez
Abstract: The goal of the research was to help identify cellular biomarkers and assess measurement technologies that will help manufacturers determine how cells react to inflammatory stimuli from different polymer matrixes and assure that tissue-engineered med ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830348

7. Biomarkers of Oxidative DNA Damage in Tissue Engineered Skin Measured by LC/MS and GC/MS Technologies
Published: 9/1/2002
Authors: H Rodriguez, M Birincioglu, C D O'Connell, Peter E. Dr. Barker, Pawel Jaruga, M. Dizdaroglu
Abstract: Tissue engineering is an emerging area of biotechnology that will provide replacement tissues for patients, as well as complex, functional biological systems for research and testing in the pharmaceutical industry. Fundamentals to many tissue-engine ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830344

8. Biomarkers of TP53 Mutation and Y-Chromosome Loss Used to Detect Cellular/Genetic Damage in Tissue Engineered Skin
Published: 9/1/2002
Authors: H Rodriguez, M A Marino, P McAndrew, Donald H Atha, Pawel Jaruga, M Birincioglu, Peter E. Dr. Barker, C D O'Connell
Abstract: Tissue engineering is an emerging area of biotechnology that will provide replacement tissues for patients, as well as complex, functional biological systems for research and testing in the pharmaceutical industry. Fundamentals to many tissue-engine ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830349

9. Cellular DNA Biomarkers for the Safety of Tissue-Engineered Medical Products Using Artificial Skin as a Model
Published: Date unknown
Authors: H Rodriguez, C D O'Connell, Peter E. Dr. Barker, M. Dizdaroglu, Donald H Atha, Pawel Jaruga, M Birincioglu, M A Marino, P McAndrew
Abstract: Fundamental to the safety of many tissue-engineered medical products is how cells respond to a given polymer when implanted into the body. Assurance of cellular stability during the manufacturing, storage and shipment of such products is crucial to ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830445

10. Characterization and Mechanism of Action of Drosophila Ribosomal Protein S3 DNA Glycosylase Activity for the Removal of Oxidatively Damaged DNA Bases
Published: 12/26/1997
Authors: W. A. Deutsch, A. Yacoub, Pawel Jaruga, T. H. Zastawny, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901592



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