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Author: pawel jaruga

Displaying records 21 to 30 of 61 records.
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21. Glutathione Depletion by Buthionine Sulfoximine Induces Oxidative Damage to DNA in Organs of Rabbits in vivo
Report Number: 901398
Published: 6/9/2009
Authors: Goksel Gokce, Gonen Ozsarlak, Gulgun Oktay, Guldal Kirkali, Pawel Jaruga, M Miral Dizdar, Zeliha Kerry
Abstract: Glutathione (GSH) exists in mammalian tissues in vivo at high concentrations and plays an important protective role against oxidatively induced damage to biological molecules including DNA. We investigated oxidatively induced damage to DNA by GSH dep ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=901398

22. Plant and fungal Fpg homologs are formamidopyrimidine DNA glycosylases but not 8-oxoguanine DNA glycosylases
Published: 5/1/2009
Authors: Scott D Kathe, Ramiro Barrantes-Reynolds, Pawel Jaruga, Michael Newton, Cynthia Burrows, Viswanath Bandaru, M Miral Dizdar, Jeffrey Bond, Susan Wallace
Abstract: Formamidopyrimidine DNA glycosylase (Fpg) and endonuclease VIII (Nei) share an overall common three dimensional structure and primary amino acid sequence in conserved structural motifs but have different substrate specificities, with bacterial Fpg pr ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=900972

23. Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice
Published: 2/1/2009
Authors: Guldal Kirkali, N de Souza-Pinto, Pawel Jaruga, V. Bohr, M Miral Dizdar
Abstract: Cockayne syndrome (CS) is a human genetic disorder characterized by sensitivity to UV radiation, neurodegeneration, premature aging among other phenotypes. CS complementary group B (CS-B) gene (csb) encodes the CSB protein (CSB) that is involved in b ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832387

24. Measurement of formamidopyrimidines in DNA
Published: 12/15/2008
Authors: Pawel Jaruga, Guldal Kirkali, M Miral Dizdar
Abstract: Formamidopyrimidines, 4,6-diamino-5-formamidopyrimidine (FapyAde) and 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyGua), are among major lesions in DNA generated by hydroxyl radical attack, UV radiation or photosensitization in vitro and in vivo. ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=832358

25. Human Polymorphic Variants of the NEIL1 DNA Glycosylase: Potential Implications for Human Health
Published: 5/25/2007
Authors: Laura Roy, Pawel Jaruga, Thomas Wood, Amanda K McCullough, M Miral Dizdar, R. Stephen Lloyd
Abstract: In mammalian cells, the repair of DNA bases damaged by reactive oxygen species is primarily initiated by a series of DNA glycosylases that include OGG1, NTH1, NEIL1 and NEIL2. To explore the functional significance of NEIL1, we recently reported tha ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830533

26. Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937
Published: 12/27/2006
Authors: S. G. Nyaga, A. Lohani, Pawel Jaruga, A. Trzeciak, M Miral Dizdar, M. K. Evans
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908180

27. Molecular Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced DNA Double-Strand Break
Published: 11/1/2006
Authors: K. Datta, Pawel Jaruga, M Miral Dizdar, R. D. Newmann, T. A. Winters
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907980

28. New functions of XPC in the protection of human skin cells from oxidative damage
Published: 9/7/2006
Authors: M. D'Errico, E. Parlanti, M. Teson, B. M. Bernardes de Jesus, P. Degan, A. Calcagnile, Pawel Jaruga, M. Bjoras, M. Crescenzi, A. M. Pedrini, J.-M. Egly, G. Zambruno, M. Stefanini, M Miral Dizdar, E. Dogliotti
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907981

29. Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer
Published: 8/1/2006
Authors: D. C. Malins, K. M. Anderson, Pawel Jaruga, C. R. Ramsey, N. K. Gilman, W. M. Green, S. W. Rostad, J. T. Emerman, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908170

30. Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound
Published: 6/1/2006
Authors: D. C. Malins, K. M. Anderson, J. J. Stegeman, Pawel Jaruga, V. M. Green, N. K. Gilman, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908169



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