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Author: pawel jaruga

Displaying records 21 to 30 of 57 records.
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21. Human Polymorphic Variants of the NEIL1 DNA Glycosylase: Potential Implications for Human Health
Published: 5/25/2007
Authors: Laura Roy, Pawel Jaruga, Thomas Wood, Amanda K McCullough, M Miral Dizdar, R. Stephen Lloyd
Abstract: In mammalian cells, the repair of DNA bases damaged by reactive oxygen species is primarily initiated by a series of DNA glycosylases that include OGG1, NTH1, NEIL1 and NEIL2. To explore the functional significance of NEIL1, we recently reported tha ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830533

22. Reduced repair of 8-hydroxyguanine in the human breast cancer cell line, HCC1937
Published: 12/27/2006
Authors: S. G. Nyaga, A. Lohani, Pawel Jaruga, A. Trzeciak, M Miral Dizdar, M. K. Evans
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908180

23. Molecular Analysis of Base Damage Clustering Associated with a Site-Specific Radiation-Induced DNA Double-Strand Break
Published: 11/1/2006
Authors: K. Datta, Pawel Jaruga, M Miral Dizdar, R. D. Newmann, T. A. Winters
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907980

24. New functions of XPC in the protection of human skin cells from oxidative damage
Published: 9/7/2006
Authors: M. D'Errico, E. Parlanti, M. Teson, B. M. Bernardes de Jesus, P. Degan, A. Calcagnile, Pawel Jaruga, M. Bjoras, M. Crescenzi, A. M. Pedrini, J.-M. Egly, G. Zambruno, M. Stefanini, M Miral Dizdar, E. Dogliotti
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907981

25. Oxidative changes in the DNA of stroma and epithelium from the female breast: potential implications for breast cancer
Published: 8/1/2006
Authors: D. C. Malins, K. M. Anderson, Pawel Jaruga, C. R. Ramsey, N. K. Gilman, W. M. Green, S. W. Rostad, J. T. Emerman, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908170

26. Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound
Published: 6/1/2006
Authors: D. C. Malins, K. M. Anderson, J. J. Stegeman, Pawel Jaruga, V. M. Green, N. K. Gilman, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=908169

27. Structural alterations in breast stromal and epithelial DNA: the influence of 8,5'-cyclo-2'-deoxyadenosine
Published: 6/1/2006
Authors: K. M. Anderson, Pawel Jaruga, C. R. Ramsey, N. K. Gilman, V. M. Green, S. W. Rostad, J. T. Emerman, M Miral Dizdar, D. C. Malins
Abstract: (5'S)-8,5'-Cyclo-2'-deoxyadenosine (S-cdA), which arises from the reaction of the hydroxyl radical (*OH) with 2'-deoxyadenosine in DNA, is a lesion comprising a base-sugar linkage that distorts the DNA backbone. This structure impedes transcription a ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=907940

28. Repair of Formamidopyrimidines in DNA Involves Different Glycosylases - Role of the OGG1, NTH1, and NEIL1 Enzymes
Published: 12/9/2005
Authors: J Hu, N de Souza-Pinto, K Haraguchi, Barbara A Hogue, Pawel Jaruga, M M Greenberg, M Miral Dizdar, V. Bohr
Abstract: 2,6-diamino-4-hydroxy-5-formamidopyrimidine (FapyG) and 4,6-diamino-5-formamidopyrimidine (FapyA), are formed abundantly in DNA of cultured cells or tissues exposed to ionizing radiation or to other free radical-generating systems. We show here that ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830498

29. Mouse NEIL1 protein is specific for excision of 2,6-diamino-4-hydroxy-5-formamidopyrimidine and 4,6-diamino-5-formamidopyrimidine from oxidatively damaged DNA
Published: 12/21/2004
Authors: Pawel Jaruga, M Birincioglu, T A Rosenquist, M Miral Dizdar
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=903209

30. Overexpression and Rapid Purification of Escherichia Coli Formamidopyrimidine-DNA Glycosylase
Published: 3/1/2004
Authors: Prasad T Reddy, Pawel Jaruga, T R O'Connor, H Rodriguez, M Miral Dizdar
Abstract: Formamidopyrimidine DNA glycosylase (Fpg) is a DNA glycosylase with an associated AP lyase activity. As a DNA repair enzyme, Fpg excises several modified bases from DNA associated with exposure to oxidizing agents such as free radicals. Experiments ...
http://www.nist.gov/manuscript-publication-search.cfm?pub_id=830402



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