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1. A Major Role for Non-Enzymatic Antioxidant Processes in the Radioresistance of Halobacterium salinarum
Published: 4/1/2011
Authors: M Miral Dizdar, Pawel Jaruga, Courtney K Robinson, Kim Webb, Amardeep Kaur, Nitin S Baliga, Allen Place, Jocelyne DiRuggiero
Abstract: Oxidative stress occurs when the generation of reactive oxygen species (ROS) exceeds the capacity of the cell‰s endogenous systems to neutralize them. We analyzed the oxidative stress responses and cellular damage of the archaeon Halobacterium salina ...

2. Accumulation of (5'S)-8,5'-cyclo-2'-deoxyadenosine in organs of Cockayne syndrome complementation group B gene knockout mice
Published: 2/1/2009
Authors: Guldal Kirkali, N de Souza-Pinto, Pawel Jaruga, V. Bohr, M Miral Dizdar
Abstract: Cockayne syndrome (CS) is a human genetic disorder characterized by sensitivity to UV radiation, neurodegeneration, premature aging among other phenotypes. CS complementary group B (CS-B) gene (csb) encodes the CSB protein (CSB) that is involved in b ...

3. Arabidopsis Thaliana Ogg1 Protein Excises 8-Hydroxyguanine and 2,6- Diamino-4-hydroxy-5-formamidopyrimidine from Oxidative Damaged DNA Containing Multiple Lesions
Published: 3/18/2003
Authors: T Morales-Ruiz, M Birincioglu, Pawel Jaruga, H Rodriguez, T. Roldan-Arjona, M Miral Dizdar
Abstract: A functional homologue of eukaryotic Ogg1 proteins in the model plant Arabidopsis thaliana has recently been cloned, isolated, and characterized [Garcia-Ortiz, M.V., Ariza, R.R., and Roldan-Arjona, T. (2001) Plant Mol. Biol. 47, 795-804]. This enzym ...

4. Biomarkers Signal Contaminant Effects on the Organs of English Sole (Parophrys vetulus) from Puget Sound
Published: 6/1/2006
Authors: D. C. Malins, K. M. Anderson, J. J. Stegeman, Pawel Jaruga, V. M. Green, N. K. Gilman, M Miral Dizdar

5. Bisphenol A leads to oxidative DNA damage and alters the damage response in mouse fibroblasts
Published: 2/18/2015
Authors: Pawel Jaruga, Natalie R Gassman, Erdem Coskun, Donna F Stefanick, Julie K Horton, M Miral Dizdar, Samuel H Wilson
Abstract: Metabolism of bisphenol A (BPA) generates reactive oxygen species causing DNA strand breaks and damaged DNA bases. Base excision repair (BER) is responsible for removing oxidatively induced DNA base lesions and for repairing single strand breaks (SSB ...

Published: 12/1/1991
Author: M Miral Dizdar

7. Characterization and Mechanism of Action of Drosophila Ribosomal Protein S3 DNA Glycosylase Activity for the Removal of Oxidatively Damaged DNA Bases
Published: 12/26/1997
Authors: W. A. Deutsch, A. Yacoub, Pawel Jaruga, T. H. Zastawny, M Miral Dizdar

8. Chlorella Virus Pyrimidine Dimer Glycosylase Excises Ultraviolet Radiation- and Hydroxyl Radical-Induced Products 4,6-Diamino-5-Formamidopyrimidine and 2,6-Diamino-4-Hydroxy-5-Formamidopyrimidine from DNA
Published: 2/1/2002
Authors: Pawel Jaruga, R Jabil, Amanda K McCullough, H Rodriguez, M Miral Dizdar, R Stephen Lloyd
Abstract: A DNA glycosylase specific for UV radiation-induced pyrimidine dimers has been identified from chlorella virus Paramecium bursaria chlorella virus-1. This enzyme (Chlorella virus Pyrimidine dimer glycosylase [cv-pdgl) exhibits a 41% amino acid identi ...

9. Clemens von Sonntag and the early history of radiation-induced sugar damage in DNA
Published: 6/2/2014
Author: M Miral Dizdar
Abstract: This article reviews the early history of radiation-induced sugar damage in DNA in dedication to Prof. Clemens von Sonntag, who recently passed away. It covers the ten years between 1968 and 1978, during which most of the work on the ionizing radiati ...

10. Copper oxide nanoparticle mediated DNA damage in terrestrial plant models
Published: 12/22/2011
Authors: Bryant C Nelson, Donald H Atha, Elijah J Petersen, Huanhua Wang, Danielle Cleveland, Richard D Holbrook, Pawel Jaruga, M Miral Dizdar, Baoshan Xing
Abstract: Engineered nanoparticles, due to their unique electrical, mechanical and catalytic properties, are presently found in many commercial products and will be intentionally or inadvertently released at increasing concentrations into the natural environme ...

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