Sheng Lin-Gibson, Ph.D.

Research Interests

Biomineralization and biomimetic approaches to generate hierarchical structures

Dental adhesives and composites: Method development for structure-function characterization

Cell (mammalian and bacteria)-material interaction: Chemical and physical influences of underlying polymeric substrate on cell response

Biopolymers and composites: Synthesis, modification, and characterization  

Research Opportunities  

NIST-NRC Postdoctoral Fellowship: 2-year fellowship sponsored by the National Research Council working at NIST. Please contact me if interested in writing proposal on dental and biomaterials research project.

• Application package requires a 3000-word original research proposal
• Stipend is $64,700 per year plus benefits and relocation expenses
• Application deadlines are Feb. 1 and Aug. 1 of each year
• Open to US citizens only  

Joint NIST-NIH Postdoctoral Fellowship: 2-year fellowship at NIST and NIH working on dental materials or biomaterials. Open to US and non-US citizens. Application deadlines are Feb. 1 and Aug. 1, requires 3000-word research proposal, contact me if interested in writing proposal.  

Professional Activities

Member, NIST Institutional Review Board, 2008 - present

Ad hoc Member: NIH Center for Scientific Review Special Emphasis Panel – Oral and Dental: Small Business Review; Oral and Dental: Small Business Review

Member, American Chemical Society, 1998-present

Member, Materials Research Society, 2009-present

Member: International Association of Dental Research, 2007-present

Member: American Association of Dental Research, 2007-present

Member: ANSI for Standard Committee for Dental Products (SCDP), 2007-present

SCDP Working Group Chair: Denture Base Resins; Adhesion: 2010-present

Program Chair: ACS Division of Polymer Chemistry (POLY) 2012-2014 

Awards and Honors

Department of Commerce Bronze Medal (2010)

National Research Council Postdoctoral Research Fellow (2001-2003)

Center for Adhesive and Sealant Science (CASS) Undergraduate Research Scholarship (1994-1997)

Louis H. and Diane E. Sharpe Undergraduate Scholarship in Adhesion Science (1996)  

Publications

• Zeiger, DN, Stafford, CM, Cheng, Y, Leigh, SD, Lin-Gibson, S, Lin, NJ "Effects of sample preparation on bacterial colonization of polymers" Langmuir, in press 2009.
• Alvine, KJ; Ding, Y, Douglas, JF; Ro, HW; Okerberg, BC; Karim, A; Lavery, KA; Lin-Gibson, S; Soles CL; "Effect of fluorosurfactant on capillary instabilities in nanoimprinted polymer patterns" Journal of Polymer Science Part B: Polymer Physics 47( 24), 2591-2600, 2009
• Sun, JR; Fang, R; Lin, N; Eidelman, N; Lin-Gibson, S. "Nondestructive quantification of leakage at the tooth-composite interface and its correlation with material performance parameters" Biomaterials, 30 (27): 4457-4462, 2009
• Lin, NJ, Lin-Gibson, S. "Osteoblast response to dimethacrylate composites varying in composition, conversion and roughness using a combinatorial approach" Biomaterials, 30 (27): 4480-4487, 2009
• Zeiger, DN; Sun, J; Schumacher, GE; Lin-Gibson S. "Evaluation of dental composite shrinkage and leakage in extracted teeth using X-ray microcomputed tomography" Dental Materials, 50:1213-1220, 2009
• Dorsey, SM; Lin-Gibson, S; Simon, CG "X-Ray Microcomputed Tomography for the Measurement of Cell Adhesion and Proliferation in Polymer Scaffolds" Biomaterials, 30:2967-2974, 2009
• Lin, NJ; Hu, H; Sung, L ; Lin-Gibson, S; "Quantification of cell response to polymeric composites using a two-dimensional gradient platform" Combinatorial Chemistry & High Throughput Screening, 12:619-625, 2009.
• Grieshaber, SE, Farran, AJE; Lin-Gibson, S; Kiick, KL, Jia, X."Synthesis and Characterization of Elastin-Mimetic Hybrid Polymers with Multiblock, Alternating Molecular Architecture and Elastomeric Properties" Macromolecules, 42:2532-41, 2009.
• Lin-Gibson, S; Sung, L; Hu, H; Forster, AM; Lin, NJ "Effects of filler type and content on mechanical properties of photopolymerizable composites determined using a two-dimensional gradient platform" Acta Biomaterialia, 5:2084-2094, 2009
• Sun JR, Lin-Gibson S. "3D Mapping of Polymerization Shrinkage Using X-ray Micro-computed Tomography to Predict Microleakage" Dental Materials, 25 314-320, 2009.
• Madsen EL; Frank GR;  Hobson MA; Lin-Gibson S; Hall TJ; Jiang J; Stiles TA "Instrument for Determining the Complex Shear Modulus of Soft-Tissue-Like Materials from 10 TO 300 Hz" Physics in Medicine and Biology, 53:19, 5313-5342, 2008.
• Hobbie EK, Lin-Gibson S, Kumar S. "Non-Brownian microrheology of a fluid-gel interface" Physical Review Letters; 7, article number 076001, 2008
• Morgan AW, Roskov KE, Lin-Gibson S, Kaplan DL, Becker ML, Simon CG. Characterization and optimization of RGD-containing silk blends to support osteoblastic differentiation. Biomaterials 29:2556-63, 2008.
• Sun JR, Lin-Gibson S. "X-ray microcomputed tomography for measuring polymerization shrinkage of polymeric dental composites" Dental Materials 24:228-34, 2008.
• Yang YY, Dorsey SM, Becker ML, Lin-Gibson S, Schumacher GE, Flaim GA, Kohn JC, Simon CG. "X-ray imaging optimization of 3D tissue engineering scaffolds via combinatorial fabrication methods" Biomaterials 29:1901-11, 2008.
• T. Kashiwagi, J. Fagan, J.F. Douglas, K. Yamamoto, A.N. Heckert, S.D. Leigh, J. Obrzut, F. Du, S. Lin-Gibson, Mi. Mu, "Relationship between dispersion metric and properties of PMMA/SWNT nanocomposites" Polymer, 48(16), 4855-4866, 2007.
• N.J. Lin, P.L. Drzal, S. Lin-Gibson. "Two-dimensional gradient platforms for rapid assessment of dental polymers: A chemical, mechanical and biological evaluation" Dental Materials, 23(10), 1211-1220, 2007.
• S. Lin-Gibson, J.A. Cooper, F.A. Landis, M.T, Cicerone, "Evaluation of Micro-Architecture and Mechanical Properties Relationships of Photopolymerized Scaffolds" Biomacromolecules, 8(5), 1511-1518, 2007.  
• J.A. Cooper Jr, W-J. Li, L.O. Bailey, S.D. Hudson, S. Lin-Gibson, K.S. Anseth, R.S. Tuan, N.R. Washburn, "Encapsulated Chondrocyte Response to Pulsatile Flow Bioreactor" Acta Biomaterialia, 3 (1), 13-21, 2007.
• E.A. Wilder, S. Guo, S. Lin-Gibson, M.J. Fasolka, C.M. Stafford, "Measuring the Modulus of Soft Polymer Networks via a Buckling-based Metrology" Macromolecules, 39(12), 4138-4143, 2006.
• F.A. Landis, J.S. Stephens, J.A. Cooper, S. Lin-Gibson, "Tissue Engineering Scaffolds Based on Photocured Dimethacrylate Polymers for in Vitro Optical Imaging" Biomacromolecules, 7, 1751-1757, 2006.
• S. Lin-Gibson, F.A. Landis, P.L. Drzal, "Combinatorial Investigation of the Structure-Properties Characterization of Photopolymerized Dimethacrylate Networks" Biomaterials, 27, 1711-1717, 2006.
• K. Zhang, C.G. Simon, Jr., N.R. Washburn, J.M. Antonucci, S. Lin-Gibson "In Situ Formation of Blends By Photopolymerization of Poly(ethylene glycol) Dimethacrylate (PEGDMA) and Polylactide (PLA)" Biomacromolecules, 6(3), 1615-1622, 2005.
• S. Lin-Gibson, S. Bencherif, J.M. Antonucci, R.L. Jones, F. Horkay, "Synthesis and Characterization of Poly(ethylene glycol) Dimethacrylate Hydrogels" Macromolecular Symposia, 227, 243-254, 2005.
• S. Lin-Gibson, R.L. Jones, N.R. Washburn, F. Horkay, "Structure-Property Relationships of Photo-polymerizable Poly(ethylene glycol) Dimethacrylate Hydrogels" Macromolecules, 38(7), 2897-2902, 2005.
• H.C.M. Byrd, S.A. Bencherif, B.J. Bauer, K.L. Beers, Y. Brun, S. Lin-Gibson, N. Sari, "Examination of the Covalent Cationization Method Using Narrow Polydisperse Polystyrene" Macromolecules, 38(5), 1564-1572, 2005.
• N.P. Patel, M.A. Hunt, S. Lin-Gibson, S. Bencherif, R.J. Spontak, "Tunable CO2 Transport Through Mixed Polyether Membranes" Journal of Membrane Science, Journal of Membrane Science, 251(1-2), 51-57, 2005. 
• A. Dundigalla, S. Lin-Gibson, V. Ferreiro, M.M. Malwitz, G. Schmidt, "Unusual Multilayered Structures in Poly(ethylene oxide)/Laponite Nanocomposite Films" Macromolecular Rapid Communications, 26, 143-149, 2005.
• G. Caliskan, D. Mechtani, J.H. Roh, A. Kisliuk, A.P. Sokolov, S. Azzam, M.T. Cicerone, S. Lin-Gibson, I. Peral "Protein and Solvent Dynamics: How Strongly are they Coupled?" Journal of Chemical Physics, 121(4), 1978-1983, 2004.
• S. Lin-Gibson, S. Bencherif, J.A. Cooper, S.J. Wetzel, J.M. Antonucci, B.M. Vogel, F. Horkay, N.R. Washburn, "Synthesis and Characterization of PEG Dimethacrylates and their Hydrogels" Biomacromolecules, 5, 1280-1287, 2004.
• E.K. Hobbie, S. Lin-Gibson, H. Wang, J.A. Pathak, H. Kim, "Ubiquity of Domain Patterns in Sheared Viscoelastic Fluids" Physical Review E, 69, 061503, 2004.
• S. Lin-Gibson, G. Schmidt, H. Kim, C.C. Han, E.K. Hobbie, "Shear-Induced Microstructural Orientation in Polymer-Clay Nanocomposite Solutions" Journal of Colloid and Interface Science, 274, 515-525, 2004.
• S. Lin-Gibson, J.A. Pathak, E.A. Grulke, H. Wang, E.K. Hobbie, "Elastic Flow Instability in Polymer-Dispersed Nanotubes" Physical Review Letters, 92(4), Art No. 048302, 2004.
• M.M. Malwitz, S. Lin-Gibson, E.K. Hobbie, P.D. Butler, G. Schmidt, "Orientation of Platelets in Multilayered Nanocomposite Polymer Films" Journal of Polymer Science, Part B, 41, 3237-3248, 2003.
• S. Lin-Gibson, G. Schmidt, H. Kim, C.C. Han, and E.K. Hobbie, "Shear-Induced Mesostructure in Nanoplatelet-Polymer Gels" Journal of Chemical Physics, 119(15), 8080-8083, 2003.
• S. Lin-Gibson, H.J. Walls, S.B. Kennedy, E.R. Welsh, "Reaction Kinetics and Gel Properties of Blocked Diisocyinate Crosslinked Chitosan Hydrogels" Carbohydrate Polymers, 54(2), 193-199, 2003.
• S. Lin-Gibson, S. Bencherif, K.L. Beers, H.C.M. Byrd "MALDI-TOF MS Characterization of Covalentaly-Cationized Polystyrene" Macromolecules, 36 (13): 4669-4671, 2003.
• E.K. Hobbie, H. Wang, H. Kim, S. Lin-Gibson, S.D. Hudson, C.C. Han, E.A. Grulke, "Orientation of Carbon Nanotubes in a Sheared Polymer Melt" Physics of Fluids, 15 (5): 1196-1202, 2003.
• S. Lin-Gibson, V. Baranauskas, J.S. Riffle, U. Sorathia, "Cresol Novolac-Epoxy Networks: Processability and Properties" Polymer, 42(26), 7389-7398, 2002.
• S. Lin-Gibson, L. Brunner, D.L. Vanderhart, B.J. Bauer, B.M. Fanconi, C.M. Guttman, W.E. Wallace, "Optimizing the Covalent Cationization Method for the Mass Spectrometry of Polyolefins" Macromolecules, 35(18), 7149-7156, 2002.
• S. Lin-Gibson, T.E. Glass, A.R. Shultz, J.S. Riffle "Controlled Molecular Weight Cresol-Formaldehyde Oligomers" Polymer, 43(7), 2017-2029, 2002.