Protein aggregation, hydrodynamic properties
The Effect of Protein Aggregation on Hydrodynamic Properties
As a first step toward understanding the complicated system of proteins aggregating in solution, we are investigating reversible protein dimerization, which is not only the most fundamental form of protein aggregation, but is also incredibly common. Using relevant structures from the Protein Data Bank and a powerful technique for computing hydrodynamic properties called ZENO, we are able to capture changes in viscosity as proteins undergo dimerization.
Materials Research Engineer
Materials Science and Engineering Division
Polymers and Complex Fluids Group