- Characterizing nanoparticle surfaces by developing synthesis routes, purification techniques, and characterization tools and methods for nanoparticle (NP) coatings, with a focus on learning how to measure and control nanomaterials at the bio-nano interface. For example, developing the use of atomic force microscopy (AFM) for quantitative self-limiting self-assembly measurements of NP surface coatings (Figure 1), or force mapping experiments combined with contact mechanics models to determine the thickness and elastic modulus of NP coatings on individual NPs including functionalized silver nanoparticles (AgNPs).
- Behavior of nanoparticles in biologically and environmentally relevant conditions that affect quantifying the fate, transformation, and persistence of NPs in-vivo or in the environment. Data sets by multiple orthogonal in-situ measurement techniques can enable structure-activity relationships to be developed that will support nanomaterial environmental health and safety (nanoEHS) risk assessment and model development, for example, by determining or controlling the aggregation and dissolution kinetics of AgNPs or nanosilver (Figure 2).
- Synthesis, purification and characterization of nanoparticles with well-defined surface chemistries to develop new routes for the self-assembly of nanomaterials, study self-limiting self-assembly for novel measurement approaches, and determine the feasibility of future candidates for reference materials, including nano-Ag or AgNPs.
Figure 1(left): Approach for measuring colloidal stability of singly dispersed AgNPs by surface plasmon resonance absorbance; Figure 2(right): Antibody mediated self-limiting self-assembly measurements of low-density protein-coated AuNPs, measured by AFM.
Awards and Honors
- Sigma Xi Member, NIST Chapter, 2009
- AFOSR STAR Team Member 2008
- National Research Council Postdoctoral Fellowship
- NSF IGERT Fellowship
- Hunter College Gene Center Predoctoral Fellowship
Nanomechanical Properties Group
2008-present: Research Chemist, Ceramics Division, NIST
2006-2008: Research Associate, Air Force Research Lab, Nanostructured and Biological Materials Branch, Wright-Patterson AFB, OH
2002-2006: Research Assistant, Hunter College, City University of New York
2000-2002: Research Assistant, University of Central Florida, Orlando, FL
Ph.D., Nanotechnology and Materials Chemistry, Graduate Center CUNY, New York, NY, 2006
M. Phil., Chemistry, Graduate Center CUNY, New York, NY, 2004
B.S., Chemistry, University of Central Florida, Orlando, FL, 2002
B.S., Molecular and Microbiology, University of Central Florida, Orlando, FL, 2002
Member of ACS, MRS, ASTM, AAAS