Dr. Christopher R. Anderton

Chris received his Bachelor of Science degree in Chemistry at the University of Colorado at Colorado Springs in 2005, graduating Cum Laude with Highest Distinction. During his undergraduate studies he participated in many research projects. His undergraduate research was primarily under the direction of Professor David J. Weiss, but he also participated in two summer National Science Foundation Research Experiences for Undergraduates at Syracuse University, under Professor Donald C. Dittmer, and at the University of California, Riverside, under Professor Francisco Zaera. Upon completing his undergraduate degree, he enrolled in the doctoral program of the Department of Chemistry at the University of Illinois at Urbana-Champaign in the fall of 2005. Chris's graduate research, under the direction of Professor Mary L. Kraft, was focused on developing complementary analytical techniques (i.e., secondary ion mass spectroscopy and atomic force microscopy) for determining lipid dynamics within model membranes.  

At NIST, Chris is currently interested in coupling surface plasmon resonance imaging with imaging mass spectrometry methods to understand cell-extracellular matrix interactions, and to chemically identify the proteins responsible for these interactions. Development of such methods would be useful in elucidating extracellular matrix properties that induce cell proliferation or differentiation, which has significant implications in bioengineering of scaffolds for organ regeneration.

Selected Publications:

1.  C.R. Anderton, B. Vaezian, K. Lou, J.F. Frisz, M. L. Kraft, "Identification of a Lipid-Related Peak Set to Enhance the Interpretation of TOF-SIMS Data from Model and Cellular Membranes," Surf Interface Anal, Submitted 2011.  

2.  C. R. Anderton, K. Lou, P. K. Weber, I. D. Hutcheon, M. L. Kraft, "Correlated AFM and NanoSIMS imaging to probe cholesterol-induced changes in phase behavior and non-ideal mixing in ternary lipid membranes," BBA-Biomembranes 2011, 1808, 307-315.  

3.  B. Vaezian, C. R. Anderton, M.L. Kraft, "Discriminating and Imaging Different Phosphatidylcholine Species within Phase-Separated Model Membranes by Principal Component Analysis of TOF-SIMS Spectral Images," Anal. Chem. 2010, 82, 10006-10014. 
 
4.  M. E. Stewart, C. R. Anderton, L. B. Thompson, J. Maria, S. K. Gray, J. A. Rogers, R. G. Nuzzo, "Nanostructured Plasmonic Sensors," Chem. Rev. 2008, 108, 494-521.