Charles H. Camp Jr.

Research Interests

My research interests lie at the intersection of science and engineering in developing and applying advanced optical techniques towards the analysis of chemical and biological specimens. Over the last decade, the availability of high-performance, high-speed lasers and detectors has greatly expanded; thus, offering exciting possibilities towards developing new optical modalities for studying light-matter interactions and to further apply these techniques towards real-world biological/chemical problems. My specific interests encompass a variety of topics, such as:

• Coherent Raman techniques such as coherent anti-Stokes Raman scattering (CARS) and stimulated Raman scattering (SRS)
• Development of novel analytical techniques based on nonlinear optical processes
• Multispectral (multivariate) data visualization and processing techniques
• The application of label-free optical techniques towards biological analysis

Currently, I am developing a high-speed coherent Raman microspectrograph that combines the speed and spatial resolution of CARS microscopy with the dense multispectral information of broadband CARS (bCARS). The system incorporates state-of-the-art sources and detectors with designed performance nearing video-rate speeds.

Dissertation Research

My dissertation research involved the development and application of the first label-free flow cytometer using multiplex CARS (MCARS). The developed system could obtain over 100 broadband spectra (~800 – 3100 cm-1) per second of flowing samples while characterizing sample morphology based on photonic elastic scatter measurements.

Selected Non-NIST Publications and Presentations

• C. H. Camp Jr., S. Yegnanarayanan, A. A. Eftekhar, and A. Adibi, "Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for the analysis of biological specimens," Optics Letters 36, 2309-2311 (2011).
• C. H. Camp, S. Yegnanarayanan, A. Eftekhar, H. Sridhar, and A. Adibi, "Multiplex coherent anti-Stokes Raman scattering (MCARS) for chemically sensitive, label-free flow cytometry", Optics Express 17, 22879 (2009).
• C. H. Camp Jr., S. Yegnanarayanan, Ali A. Eftekhar, and Ali Adibi, "Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS) for biological analysis," IEEE Photonics Conference, Arlington, Virginia, October 9-13, 2011.
• C. H. Camp Jr., S. Yegnanarayanan, Ali A. Eftekhar, and Ali Adibi, "Label-free flow cytometry using multiplex coherent anti-Stokes Raman scattering (MCARS)," microCARS, Gothenburg, Sweden, May 9-11, 2010. Invited presentation.