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|Author(s):||Denis E. Bergeron; Jeffrey T. Cessna; Daniel B. Golas; Rheannan K. Young; Brian E. Zimmerman;|
|Title:||Dose calibrator manufacturer-dependent bias in assays of 123I|
|Published:||March 26, 2014|
|Abstract:||Calibration factors for commercial ionization chambers (i.e. dose calibrators) were determined for a solution of 123I; the activity was based on the 1976 NBS standard. A link between the NIST standard and the International Reference System (SIR) was established. The two major U.S. dose calibrator manufacturers recommend oppositely biased calibration factors, giving a spread of 11.3 % in measured activities. With modern quantitative imaging techniques capable of ≤ 10 % accuracy, this bias for a SPECT nuclide is highly significant.|
|Citation:||Applied Radiation and Isotopes|
|Pages:||pp. 79 - 86|
|Keywords:||Ionization chamber, dose calibrator, I-123, secondary standard, quantitative imaging|
|Research Areas:||Medical Physics|
|DOI:||http://dx.doi.org/10.1016/j.apradiso.2014.03.018 (Note: May link to a non-U.S. Government webpage)|