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Publication Citation: Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications.

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Author(s): Elissa H. Williams; John A. Schreifels; Mulpuri V. Rao; Albert Davydov; Vladimir P. Oleshko; Nancy J. Lin; Kristen L. Steffens; Sergiy Krylyuk; Kristine A. Bertness; Amy Manocchi; Yaroslav Koshka;
Title: Selective Streptavidin Bioconjugation on Si and SiC nanowires for Biosensor Applications.
Published: January 14, 2013
Abstract: A functionalization method for the specific and selective immobilization of the streptavidin (SA) protein on semiconductor nanowires (NWs) was developed. Silicon (Si) and silicon carbide (SiC) NWs were functionalized with 3-aminopropyltriethoxysilane (APTES) and subsequently biotinylated for the conjugation of SA. Field-emission scanning electron microscopy (FESEM), X-ray photoelectron spectroscopy (XPS), high-resolution transmission electron microscopy (HRTEM), atomic force microscopy (AFM), and fluorescence microscopy were utilized to study each functionalization step on the Si and SiC NWs.
Citation: Journal of Materials Research
Volume: 28
Issue: 1
Pages: pp. 68 - 77
Keywords: biosensor; nanowires; surface chemistry
Research Areas: Nanowires, Nanomaterials, Thin-Films
DOI: http://dx.doi.org/10.1557/jmr.2012.283  (Note: May link to a non-U.S. Government webpage)