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Publication Citation: Effect of Polymeric Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells

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Author(s): Girish Kumar; Marian F. Young; Carl G. Simon Jr;
Title: Effect of Polymeric Scaffold Structure on Osteogenic Differentiation of Human Bone Marrow Stromal Cells
Published: December 17, 2010
Abstract: Structural properties of polymeric scaffolds for bone tissue engineering play key role in directing osteogenesis. These properties depend on the chemical nature and the fabrication process of biomaterial. There are many protocols for fabricating scaffolds for bone tissue engineering applications which afford control over scaffold topology. In addition, much work has demonstrated that cell differentiation is sensitive to topology at sizes ranging from nano- to micro- to macroscale1. Thus, we have investigated the effect of different scaffold topologies on differentiation of human bone marrow stromal cells (hBMSCs).
Conference: TERMIS
Pages: 1 pp.
Location: Orlando, FL
Dates: December 5-7, 2010
Keywords: tissue engineering; polymer scaffold; stem cell; cell differentiation; bone; osteogenesis
Research Areas: Polymers, Biocompatability, Combinatorial Methods, Materials Science, Biomaterials, Bioscience & Health, Advanced Materials
PDF version: PDF Document Click here to retrieve PDF version of paper (525KB)