| Author(s): |
Santanu S. Kundu; Atul Bhangale; William E. Wallace III; Kathleen M. Flynn; Richard Gross; Kathryn L. Beers; |
| Title: |
IMMOBILIZED ENZYME CATALYZED POLYMERIZATION REACTIONS IN MICROREACTORS |
| Published: |
January 01, 2010 |
| Abstract: |
Application of microreactor technologies enable improved safety, selectivity and yield in a range of chemical reactions in addition to new measurement methods that are often faster, cheaper and more accurate than traditional methods. In this study we have considered a model system, Candida antartica Lipase B (CAL B) catalyzed polycaprolactone synthesis from -caprolactone. CAL B was immobilized on polymethyl methacrylate support and was loaded in the microchannel reactors. Raman spectroscopy, Nuclear Magnetic resonance (NMR) and Gel permeation Chromatography (GPC) were used to characterize the reaction products. The monomer conversion in microreactors was faster than that observed in the batch reactors. |
| Proceedings: |
American Chemical Society Spring 2010 National Meeting |
| Volume: |
51 |
| Issue: |
1 |
| Pages: |
pp. 745 - 746 |
| Location: |
San Francisco, CA |
| Dates: |
March 21-25, 2010 |
| Keywords: |
microreactor, enzyme catalysis, ring opening polymerization |
| Research Areas: |
Combinatorial Methods, Characterization, Materials Science, Microfluidics |
| PDF version: |
 Click here to retrieve PDF version of paper (718KB) |
