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Dr.
Milton Corn is Associate Director of the National Library of
Medicine and Director of the Library's grant programs, a principal
source of funding for medical informatics research and training
in the U.S. He is a graduate of Yale College and Yale Medical School.
He was trained in internal medicine at Harvard's Peter Bent Brigham
Hospital, and in hematology at Johns Hopkins. Most of his academic
career was spent at Georgetown University School of Medicine, where
he held the appointment of Professor of Medicine. In 1984-85 he
was Medical Director of Georgetown University Hospital, and subsequently
served for four years as Dean of Georgetown's Medical School. He
joined the National Library of Medicine in 1990.
Dr.
Monica Crubézy is a research scientist in the Stanford
Medical Informatics laboratory at Stanford University. Her research
focuses on the modeling of libraries of reusable software components
and their integration with domain ontologies to build problem-solving
applications. In particular, Dr. Crubézy builds tools for
mapping and mediating data and knowledge among components of ontology-based
systems. Dr. Crubézy graduated from the Ecole Polytechnique
Féminine, France, in general engineering and computer science.
She has a PhD in computer science from the University of Nice-Sophia
Antipolis, France and the Institut National de Recherche en Informatique
et Automatique (INRIA), France. Her research thesis focused on the
automatic selection, planning and execution of software components
in the domain of medical image processing. Visit her website at:
http://smi.stanford.edu/people/crubezy/.
Dr.
David Benton is Director, Knowledge Integration and Discovery
Systems in the Informatics and Knowledge Management Department,
R&D IT, GlaxoSmithKline. His interests include the application
of intelligent information integration approaches, ontologies, component
architectures, and visualization systems to priority drug discovery
problems. Prior to joining SmithKlineBeecham in 1997, he was Director,
Genome Informatics Program, National Human Genome Research Institute,
National Institutes of Health. And, prior to joining NIH in 1990,
he was Manager of the GenBank project at IntelliGenetics, Inc (1987-1990)
and a staff researcher at the ARCO Plant Cell Research Institute
(1980-1987). In addition, since 1997, he has served as Co-Chair
of the Life Sciences Research Domain Task Force, within the Object
Management Group. This consortium of pharmaceuticals, biotechs,
software vendors, and academics seeks to develop industry standards
to support software interoperability for bioinformatics, genomics,
cheminformatics, structural biology, and related domains.
Dr.
Gary Bader is currently a post-doctoral fellow in the lab of
Dr. Chris Sander at the Computational Biology Center at Memorial
Sloan-Kettering Cancer Center in New York City. Previously, Gary
completed a Ph.D. in the lab of Dr. Christopher Hogue in the Department
of Biochemistry at the University of Toronto and the Program in
Proteomics and Bioinformatics at the Samuel Lunenfeld Research Institute
at Mount Sinai Hospital in Toronto. His thesis research involved
helping to conceptualize the Biomolecular Interaction Network Database
(BIND) with Dr. Hogue, originally an idea of Dr. Tony Pawson. Gary
implemented the original version of BIND and used it for visualization
and analysis of large protein and genetic interaction networks generated
by new high-throughput proteomics and genomics techniques. He received
a B.Sc. in Biochemistry from McGill University in Montreal as well
as the equivalent of an undergraduate major in computer science
from McGill University and University of Toronto.
Dr.
Bruno Sobral, founding Director of the Virginia Bioinformatics
Institute and Professor of Plant Physiology, Pathology and Weed
Science at Virginia Tech, has a long-standing personal interest
in reverse engineering living systems, especially in agriculturally
or environmentally important organisms. His main wetlab research
entails using comparative genomics, bioinformatics and proteomics
to understand host-pathogen-environment interactions. His cyberinfrastructure
research is focused on engineering robust and open frameworks for
data and on tool interoperability and integration for Life Sciences.
Dr. Sobral received his Ph.D. in Genetics from Iowa State University
in 1989, and his Agronomic Engineer degree from the Federal University
of Viçosa in Brazil in 1985. He has worked in a number of
international research organizations, including Genetica Americas
(La Jolla, 1995-98), the Center for Applications of Molecular Biology
to International Agriculture (Canberra, 1993-96), and the California
Institute of Biological Research (CIBR, La Jolla, CA; 1991-95);
and just prior to moving to Virginia, he was Vice President of Scientific
Programs at the National Center for Genome Resources in Santa Fe.
He has simultaneously held adjunct faculty appointments at New Mexico
State University, University of New Mexico, and San Diego State
University.
Dr.
Michael W. Vannier is Professor of Radiology at the University
of Iowa, College of Medicine and was Special Assistant to the Director
of the Biomedical Imaging Program at the National Cancer Institute
from 2001 to 2003. Dr. Vannier was the Georgia Eminent Scholar in
Medical Imaging at the Emory University School of Medicine in Atlanta,
Georgia from 1994 to 1996, and served as Vice-Chairman for Research
at the Mallinckrodt Institute of Radiology from 1992 to 1994. Dr.
Vannier was Professor of Radiology at the Mallinckrodt Institute
of Radiology from 1989 to 1997, as an Assistant Professor of Radiology
and Surgery at the Washington University School of Medicine in St.
Louis, Missouri from 1983 to 1997, and Editor-in-Chief of the IEEE
Transactions on Medical Imaging from 1984 to 2002. Dr. Vannier is
a Fellow of the American College of Radiology and a Fellow of the
American Institute of Medical and Biological Engineering. Dr. Vannier
has been a director of Vital Images, Inc. (NASDAQ: VTAL) since December
1997.
Larry
Reeker is Senior Computer Scientist in the Information Technology
Laboratory office at the National Institute of Standards and Technology.
He handles a National Science Foundation-NIST program in summer
information technology research for undergraduates and serves as
a liaison to other government agencies, both directly and through
the National Coordinating Office for Information Technology Research
and Development, is an advisor to the Army Science board and a member
of the Research Management Board for the Army Research Laboratory's
Advanced Decision Systems Program. He was formerly a professor at
Ohio State, Arizona, Queensland (Australia) and Tulane, heading
a CS department at the last two. His published papers, research,
and teaching have been in artificial intelligence, linguistics and
natural language processing, models of learning, program languages
and environments, theory of computing, knowledge engineering, and
software engineering. Outside of academia, he was a VP at a 4000-employee
technical corporation, research staff member at a "think tank",
and program director at the National Science Foundation, prior to
joining NIST in 1998. Professional activities have included serving
on the ACM's governing board, voluntary standards activities and
university accreditation work through IEEE, on advisory committees
for educational institutions, and reviewing research proposals for
multiple agencies in the U.S and abroad. He is currently doing research
in knowledge modeling and testing. His undergraduate degree is from
Yale (Math, Philosophy, Linguistics) and his PhD from Carnegie Mellon
in Computer Science.
Dr.
Kenneth Buetow received a B.A. in Biology from Indiana University
in 1980, and a Ph.D. (1985) in Human Genetics from the University
of Pittsburgh. From 1986 to 1998 Dr. Buetow was at the Fox Chase
Cancer Center in Philadelphia, where his group generated and electronically
distributed the human genetic map. Dr. Buetow serves a dual role
for the National Cancer Institute. He is the Director of the NCI
Center for Bioinformatics (NCICB) and Chief of the Laboratory of
Population Genetics (LPG). His research interests include the application
of genetics and genomics tools to understand the genetic basis of
complex traits. Dr. Buetow has spearheaded efforts of the Genetic
Annotation Initiative (GAI), an attempt to identify variant forms
of the cancer genes identified through the NCI Cancer Genome Anatomy
Project (CGAP). He is particularly interested in genetic variations
that make individuals more susceptible to liver, lung, prostate,
breast, and ovarian cancer. His group combines computational tools
with bench-top laboratory findings to understand how genes and environment
interact to increase cancer risk. The NCICB coordinates and deploys
informatics in support of NCI research initiatives. Its goal is
to maximize interoperability and integration of NCI research and
its related information. The Center participates in the evaluation
and prioritization of the NCI's bioinformatics research portfolio,
conducts or facilitates research that is required to address the
NCICB's mission, serves as the locus for strategic planning to address
the NCI's expanding research initiative's informatics needs, establishes
information technology standards (both within and outside of NCI),
and communicates, coordinates, or establishes information exchange
standards. The LPG conducts human genetic and genomics research,
both at the bench and using informatics tool. The major goal of
this research program is to apply and extend human genetic analysis
methods and resources to better understand the genetics of complex
phenotypes, specifically human cancer.
Dr.
Richard Hilderbrandt joined the National Science Foundation
in 1987 as the Program Director for Theoretical and Computational
Chemistry. In 1999 he led the NSF-wide Knowledge and Distributed
Intelligence Initiative, and in 2000 he joined the CISE Directorate
as the first Program Director for Information Technology Research.
Since September of 1999 he has served as the Program Director for
the Partnerships for Advanced Computational Infrastructure and has
managed the NSF Terascale Initiative.
Dr.
Ian Foster is Associate Director of the Mathematics and Computer
Science Division at Argonne National Laboratory and Professor of
Computer Science at the University of Chicago. The Distributed Systems
Lab that he heads at Argonne and Chicago is home to the Globus Toolkit,
the open source software that has emerged as the de facto standard
for Grid computing. He has published five books and over 200 articles
and technical reports on various topics relating to programming
languages, parallel computing, and distributed systems. He is a
fellow of the British Computer Society, and has received numerous
awards for his research, including the GII Next Generation Award
and the British Computer Society's Lovelace Medal.
Dr.
Andrew Grimshaw, Avaki Founder & Chief Technology Officer
Long considered one of the true visionaries in the distributed computing
movement, Dr. Andrew Grimshaw is the Founder and Chief Technology
Officer of Avaki. After receiving his Ph.D. from the University
of Illinois at Urbana-Champaign, he joined the University of Virginia
as an assistant professor of Computer Science, and became a full
professor in 1998. As the chief designer and architect of both the
Mentat and Legion projects, and the author of over 50 publications
and book chapters, Dr. Grimshaw is a strong believer in open standards
and industry-wide collaboration. He is a founding member of the
Global Grid Forum (GGF), where he serves on the Steering Committee
and works within the Open Grid Service Infrastructure Working Group
(OGSI-WG). An avid presenter on the global lecture circuit, Dr.
Grimshaw has spoken at hundreds of conferences and tradeshows worldwide.
In addition to his role of visionary and strategist at Avaki, Dr.
Grimshaw has worked on numerous industry initiatives such as the
National Partnership for Advanced Computational Infrastructure (NPACI)
Executive Committee, the Department of Defense High Performance
Computing Modernization Office (DoD HPCMO) Program Environment &
Training (PET) Executive Committee, the National Institute of Standards
and Technology (NIST) Information Technology Library (ITL) review
panel, the National Aeronautics and Space Administration (NASA)
Center of Excellence in Space Data and Information Sciences (CESDIS
) review panel, and the editorial board of the Institute of Electrical
and Electronics Engineers (IEEE) Transactions on Parallel and Distributed
Computing.
Dr.
Arlin Stoltzfus uses computational and analytical tools to study
the evolution of genes, proteins, and genomes. Before becoming a
computational biologist, he received laboratory training in bacterial
genetics and molecular biology. Most of Stoltzfus's research is
in two areas, the evolution of introns, and the role of mutation
biases in sequence evolution. This research is motivated by classic
evolutionary questions: Do trends and parallelisms reflect external
factors (natural selection) or internal factors (mutation)? How
much of evolution is adaptive? Do complex functions arise incrementally
by the adaptive accumulation of small-effect variants, or must one
invoke other mechanisms?
Dr.
Atul Butte is currently on staff in the Children's Hospital
Informatics Program, is a practicing pediatric endocrinologist at
Children's Hospital, Boston, and is an Instructor at Harvard Medical
School. Dr. Butte has authored 25 publications in bioinformatics,
medical informatics, and molecular diabetes and has delivered more
than 30 presentations world-wide on bioinformatics, including four
at the National Institutes of Health. During his research work under
Dr. Isaac Kohane, he developed a novel methodology for analyzing
large data sets of RNA expression, called Relevance Networks. Dr.
Butte has won several awards for his research, which is supported
by grants from NCI, NIDDK, NHLBI, NINDS, NIAID, NLM, the Endocrine
Fellows Foundation, the Genentech Center for Clinical Research and
Education, the Lawson Wilkins Pediatric Endocrinology Society, and
Merck. Along with Isaac Kohane and Alvin Kho, Dr. Butte has co-authored
one of the first books on microarray analysis titled "Microarrays
for an Integrative Genomics" published by MIT Press. Dr. Butte
received his undergraduate degree in Computer Science from Brown
University in 1991. He graduated from the Brown University School
of Medicine in 1995, during which he worked as a research fellow
at NIDDK through the Howard Hughes/NIH Research Scholars Program.
He completed his residency in Pediatrics and Fellowship in Pediatric
Endocrinology in 2001, both at Children's Hospital, Boston.
Keith
Elliston, PhD. brings to Genstruct compelling experience as
a molecular biologist, a computer technologist, and an entrepreneur.
He was Chairman, President and CEO of Viaken Systems Inc., a discovery
informatics company he co-founded in 1999. Prior to Viaken, Keith
was the Sr. VP of R&D, President of the Bioinformatics Division,
and Chief Scientific Officer at Gene Logic. While at Gene Logic,
he secured and managed six pharmaceutical discovery partnerships
worth more than $350M in potential revenues, and was instrumental
to the Series C and initial public offerings of the company. Keith
founded the bioinformatics and genomics efforts of Bayer AG, where
he was the world-wide head of bioinformatics, and the Section Head
for Genomics. Prior to Bayer, he spent 10 years with Merck &
Co. Inc., where he started one of the first computational molecular
biology groups in the pharmaceutical industry, and where he founded
and directed the department of bioinformatics. He also co-founded
and directed the Merck Gene Index project, Merck's first genomics
effort, which resulted in over 400,000 Genbank entries and was responsible
for the initial discovery of more than 30,000 human genes. Keith
has also been an advisor to Oak Investment partners and other biotechnology
venture capital groups, and has participated in the early stage
development of a number of biotech companies, including Sequana
Therapeutics, Structural Genomics and Spotfire. Keith received an
M.S. in Genetics from the University of Minnesota, and a Ph.D. in
Molecular Genetics from Rutgers University.
Dr.
John Doyle is a Professor in Control and Dynamical Systems,
BioEngineering, and Electrical Engineer at Caltech. His current
research interests are in theoretical foundations for complex networks
in engineering and biology, as well as multiscale physics, focusing
on the interplay between robustness, feedback, control, dynamical
systems, computation, communications, and statistical physics. Prize
papers include the IEEE Baker (also ranked in the top 10 ``most
important'' papers world-wide in pure and applied mathematics from
1981-1993), the IEEE AC Transactions Axelby (twice), and the AACC
Schuck. Individual awards include the IEEE Control Systems Award
and the IEEE Centennial Outstanding Young Engineer. He has held
national and world records and championships in various sports.
Dr.
Srikanta P. Kumar received the B.S. degree (Honors) in physics
from Bangalore University, Bangalore, India, in 1971, and M.E. degrees
from the Indian Institute of Science, Bangalore, in 1974 and 1976,
respectively, and the Ph.D. degree in engineering and applied science
from Yale University, New Haven, CT, in 1981. Dr. Kumar is currently
a Program Manager at the Defense Advanced Research Projects Agency
(DARPA), and Senior Technical Advisor in the Information Technology
Laboratory of the National Institute of Standards and Technology
(NIST). At DARPA, he formulated the technical framework for research
and technology development for several programs, including the sensor
information technology (SensIT) program, the network modeling and
simulation (NSM) program, and the bio-computation (BioComp) program.
He has been also responsible for the management and execution of
these programs. Dr. Kumar was a tenured faculty member in the Electrical
and Computer Science and Engineering Department, Northwestern University,
Evanston, IL, from 1985 to 1998. While at Northwestern, he was the
co-founder and founding Director of the Executive Masters Program
on Information Technology, an interdisciplinary program involving
the McCormick School of Engineering, the Kellogg Business School,
and the Communications Department. He served on the faculty of Electrical,
Computer, and Systems Engineering Department, Rensselaer Polytechnical
Institute, Troy, NY, from 1982 to 1985, and the State University
of New York at Buffalo from 1981 to 1982. He has held visiting professor
positions at Johns Hopkins University and the University of Maryland
campuses at College Park and Baltimore County. He has published
more than 80 technical papers.
Dr.
Bob Eisenberg is the Bard Professor and Chairman, Dept. of Molecular
Biophysics and Physiology, Rush Medical Center, Chicago. His research
focuses on quantitative computational biology, in particular on
the development of mathematical models for multi-scale analysis
of ion channels, seeking to predict the current through the channel,
in a range of solutions of different composition, over a range of
voltages. After single channel recording was discovered, he (along
with Rick Levis and Jim Rae) designed the AxoPatch patch clamp amplifier
which is used by most workers in the field to this day. He served
as Chairman of the Physiology Study Section of the NIH for several
years, and Director of Research (etc) for the American Heart Association
(Chicago Branch). Dr. Eisenberg received his A.B. (summa cum laude)
from Harvard College, and a Ph.D. from the University College London.
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