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Diagnostics Programs & Projects

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Reference Measurement Procedures and Materials for Creatinine
Last Updated Date: 03/19/2015

Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by … more

Development of Standard Reference Materials for Vitamins B6 and B12 in Human Serum
Last Updated Date: 02/27/2015

Vitamins are essential to normal functioning of the human body because they serve as co-factors for important biological processes. Deficiencies in … more

Development of Reference Methods and Reference Materials for Clinical Diagnostic Markers
Last Updated Date: 02/09/2015

The accuracy of clinical diagnostic measurements is essential for reliable diagnosis and cost-effective treatment of disease. NIST's involvement in … more

Development of SRMs for Accurate Assessment of Exposure to Toxic Elements and Anions
Last Updated Date: 02/03/2015

As part of a multi-year interagency agreement between the National Institute of Standards and Technology (NIST) and the Centers for Disease Control … more

Development of SRM 2669 for Accurate Assessment of Arsenic Exposure
Last Updated Date: 01/28/2015

The National Institute of Standards and Technology (NIST), in collaboration with the Centers for Disease Control and Prevention (CDC), has … more

Superresolving Optical Microscopy
Last Updated Date: 01/23/2015

Light microscopy is a widely used analytical tool because it provides non-destructive, real-time, three-dimensional imaging with chemical and … more

Fatty Acids in Human Serum and Plasma Quality Assurance Program
Last Updated Date: 01/20/2015

The National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) have … more

Evaluating Measurement Quality of Microfluidic Cell-based Assays
Last Updated Date: 01/14/2015

Microfluidic technologies show promise as miniaturized, portable platforms for cell assays, but must be tested to establish confidence of … more

Controlling Microfluidic Cell Culture Environments
Last Updated Date: 01/14/2015

NIST has taken advantage of recent technological advances to develop polymer microfluidic cell culture systems that provide a level of control … more

Bioimaging
Last Updated Date: 12/01/2014

Our goal is to develop methods and materials for imaging-based characterization of molecular signatures that occur during cellular proliferation, … more

Clinical Quality Assurance Program
Last Updated Date: 09/16/2014

The National Institute of Standards and Technology (NIST) has established a Clinical Quality Assurance Program (ClinQAP) to support the … more

Tandem Mass Spectral Library
Last Updated Date: 07/10/2013

The National Institute of Standards and Technology is responsible for an evaluated, tandem mass spectral library as an extension of the … more

Digital PCR
Last Updated Date: 04/26/2013

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR … more

SRM for Huntington CAG Repeat
Last Updated Date: 03/15/2013

Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by … more

Genome in a Bottle Consortium
Last Updated Date: 03/15/2013

NIST has organized the "Genome in a Bottle Consortium" to develop the reference materials, reference data, and reference methods needed to assess … more

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