DNA Science Group

Development of Biomarker-based Systems for Cancer Detection and Therapy — Biomarkers play an increasingly important role in disease detection and treatment. As one of the Biomarker Reference Laboratories (BRLs) in the Early Detection Research Network (EDRN) - an … Development of SRMs for Serum Proteomics — Serum proteomics, the detection and measurement of as many proteins in a serum sample as possible, could be an important element of personalized medicine enabling diagnosis of early stages of … Fundamental Interaction Mechanisms of Engineered Nanomaterials with DNA — We utilized isotope-dilution liquid chromatography/mass spectrometry (LC/MS) to determine the levels of the oxidatively damaged DNA bases, 8-hydroxydeoxyguanosine (8-OH-dG) and … Protection Against Ionizing Radiation in Extreme Radiation-Resistant Microorganisms — We measured the levels of modified DNA bases following ү-irradiation of the halophilic archaeon, Halobacterium sp. str. NRC-1. In this first study to quantify DNA base modification in a … Standards for Immuno-Histochemical Imaging: A Biomarker Protein Expression Chip — Immunohistochemistry (IHC) is used to visualize antigens in tissue sections by specific antigen-antibody interactions, an advantage over traditionally used staining techniques that can identify …

• Addressing Y-Chromosome Short Tandem Repeat(Y-STR) Allele Nomenclature
• The Escherichia coli YdcF binds S-adenosyl-L-methionine and adopts an α/β fold characteristic of nucleotide-utilizing enzymes
• Semiconductor nanocrystal conjugates, FISH and pH