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Chemistry Programs & Projects

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Traceability for Industrial Irradiator
Last Updated Date: 02/26/2013

U.S. manufacturers have contended for decades that traceability to national standards for industrial irradiation applications is best achieved by … more

High Rate Testing
Last Updated Date: 02/22/2013

This project involves sample geometry and metrological development for high rate servohydraulic testing. (Content to be uploaded soon) more

Testing of Radiation Detection Systems
Last Updated Date: 12/12/2012

NIST is working together with the Department of Homeland Security (DHS) Domestic Nuclear Detection Office (DNDO) in testing radiation detection … more

Traceability in Molecular Spectrophotometry
Last Updated Date: 11/20/2012

Standard Reference Materials (SRMs) and NIST Traceable Reference Materials (NTRMs) for UV/visible/NIR spectrophotometry are certified transfer … more

Improved Benchtop Connectivity to Complex Microfluidic Devices
Last Updated Date: 10/10/2012

Despite their promise to enable high-throughput science and discovery, microfluidic devices have not yet been broadly adopted. An important … more

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity
Last Updated Date: 10/10/2012

The most commonly used cell-based assays for measuring cytotoxicity often show poor reproducibility, require 24 h to complete, and rely on a … more

26plex Autosomal Short Tandem Repeat Assay
Last Updated Date: 10/08/2012

A short tandem repeat (STR) multiplex assay was developed with 25 autosomal loci plus the sex-typing locus amelogenin for a total of 26 amplified … more

Rapid Multiplex PCR
Last Updated Date: 10/08/2012

Forensic DNA typing is currently conducted in approximately eight to ten hours. The process includes DNA extraction, quantitation, multiplex PCR … more

Chemical/Biochemical Microsensor Science
Last Updated Date: 10/02/2012

The Process Sensing Group at NIST is investigating a range of fundamental and technological issues related to next-generation chemical and … more

Assessing the Internal Structure and Composition of Climatically-Relevant Atmospheric Particles
Last Updated Date: 10/02/2012

Atmospheric particles with long atmospheric lifetimes affect Earth's radiative balance. These particles typically consist of multiple chemical … more

Energy Determination of X-Ray Transition Energies Using the NIST TES Microcalorimeter Detector
Last Updated Date: 10/02/2012

Previous efforts to produce a comprehensive tabulation of atomic x-ray transition energies have been hampered by the fact that a) detectors having … more

Site-Specific Bioimaging
Last Updated Date: 10/02/2012

In collaboration with scientists at the Laboratory for Cell Biology (LCB) within the National Cancer Institute (NCI) of the National Institutes of … more

Polymer Microspheres By Annular Co-Flow Extrusion
Last Updated Date: 10/02/2012

Well characterized test materials are essential for validating the performance of trace explosive detection systems. Particle size, chemical … more

Next-Generation Metrology for Drug Delivery Systems
Last Updated Date: 10/02/2012

A critical metrology issue for pharmaceutical industries is the application of analytical techniques to the characterization of drug delivery … more

Rapid Isotopic Screening
Last Updated Date: 10/02/2012

We have exploited the built-in functionality of a secondary ion mass spectrometer to provide the capability to screen the enrichment levels of a … more

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