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Chemistry Programs & Projects

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Fundamental Chemical Metrology
Last Updated Date: 10/22/2012

The Chemical Sciences Division serves as the Nation’s reference laboratory for chemical compositional measurements and standards to enhance U.S. … more

High-Precision Isotopic Reference Materials
Last Updated Date: 10/22/2012

Recent innovative advances in the design and manufacture of isotope ratio mass spectrometers (IRMS) have revolutionized the study of natural and … more

Reference Measurement Procedures and Materials for Creatinine
Last Updated Date: 10/22/2012

Chronic kidney disease (CKD) is a growing problem in the U.S., and current estimates suggest that more than 20 million Americans are affected by … more

Development of a Standard Reference Material for Metabolites in Plasma
Last Updated Date: 10/22/2012

Metabolomics is a relatively new field that builds upon work in genomics and proteomics. Metabolomics can provide a unique perspective on the … more

Fatty Acid Methods and Measurements
Last Updated Date: 10/22/2012

The Chemical Sciences Division is working to develop natural-matrix and solution-based SRMs that are characterized for fatty acid composition. The … more

Proficiency Test Results
Last Updated Date: 10/22/2012

Proficiency Test (PT) results are available at no cost to customers who have tested SRMs 2092, 2096, and 2098.   A PT result serves as a means to … more

Measurements and Standards for Botanical Dietary Supplements
Last Updated Date: 10/19/2012

As part of a multi-year interagency agreement among the National Institute of Standards and Technology (NIST), the National Institutes of Health's … more

Standard Solution SRMs Provide Traceability for Millions of Measurements
Last Updated Date: 10/18/2012

For decades, NIST has provided the SRM 3100 series single-element standard solutions. The certified values are traceable to the International … more

NIST SRM for Reproducible Analyses of Single-Walled Carbon Nanotubes
Last Updated Date: 10/16/2012

Carbon nanotubes (CNTs) are one of the first major nanoscale manufactured products to enter the market. Therefore, reliable and reproducible … more

Improved Benchtop Connectivity to Complex Microfluidic Devices
Last Updated Date: 10/10/2012

Despite their promise to enable high-throughput science and discovery, microfluidic devices have not yet been broadly adopted. An important … more

Cell-based Assay for Mechanistically-based Prediction of Cytoxicity
Last Updated Date: 10/10/2012

The most commonly used cell-based assays for measuring cytotoxicity often show poor reproducibility, require 24 h to complete, and rely on a … more

Mercury Vapor Pressure Correlation
Last Updated Date: 10/09/2012

An apparent difference between the historical mercury vapor concentration equations used by the mercury atmospheric measurement community and a … more

Neutron Imaging for Health, Environment, and the Hydrogen Economy
Last Updated Date: 10/09/2012

Quantitative imaging tools enhance our ability to understand biological systems and achieve efficient hydrogen fuel cells. Today's metrological … more

Potential Primary Measurement Tool for the Quantification of DNA
Last Updated Date: 10/09/2012

The accurate mass determination of DNA and other nucleic acids is of critical importance in many clinical diagnoses and in forensic and molecular … more

Study of Microheterogeneity in Solid Reference Materials
Last Updated Date: 10/09/2012

Microbeam X-ray fluorescence (µXRF) has been used nondestructively to investigate elemental heterogeneity by constructing two-dimensional maps of … more

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