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Chemical Analysis Programs & Projects

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Tandem Mass Spectral Library
Last Updated Date: 07/10/2013

The National Institute of Standards and Technology is responsible for an evaluated, tandem mass spectral library as an extension of the … more

Chemical/Biochemical Microsensor Science
Last Updated Date: 10/02/2012

The Process Sensing Group at NIST is investigating a range of fundamental and technological issues related to next-generation chemical and … more

Assessing the Internal Structure and Composition of Climatically-Relevant Atmospheric Particles
Last Updated Date: 10/02/2012

Atmospheric particles with long atmospheric lifetimes affect Earth's radiative balance. These particles typically consist of multiple chemical … more

Energy Determination of X-Ray Transition Energies Using the NIST TES Microcalorimeter Detector
Last Updated Date: 10/02/2012

Previous efforts to produce a comprehensive tabulation of atomic x-ray transition energies have been hampered by the fact that a) detectors having … more

Site-Specific Bioimaging
Last Updated Date: 10/02/2012

In collaboration with scientists at the Laboratory for Cell Biology (LCB) within the National Cancer Institute (NCI) of the National Institutes of … more

Next-Generation Metrology for Drug Delivery Systems
Last Updated Date: 10/02/2012

A critical metrology issue for pharmaceutical industries is the application of analytical techniques to the characterization of drug delivery … more

Rapid Isotopic Screening
Last Updated Date: 10/02/2012

We have exploited the built-in functionality of a secondary ion mass spectrometer to provide the capability to screen the enrichment levels of a … more

Trace Narcotics Detection
Last Updated Date: 10/02/2012

A large suite of illicit drug samples were analyzed using IMS to evaluate the selectivity and sensitivity of the technique. The sample suite … more

Molecular Orbital Structure of Energetic Nitrogen Compounds from X-Ray Emission Spectroscopy
Last Updated Date: 10/02/2012

When chemical compounds of low-Z elements are excited by x-rays, the ionized core states are filled from the valence band. The molecular orbital … more

Milli X-ray Fluorescence X-ray Spectrum Imaging Technique Development
Last Updated Date: 10/02/2012

Significant improvements were made in the area of technique development for Eagle III mXRF since its initial installation in 2007. The diverse … more

Evaluation of the Extent of Electron Scattering in a Low Vacuum Scanning Electron Microscope
Last Updated Date: 10/02/2012

Low vacuum scanning electron microscopes utilize gas molecules in the specimen chamber to neutralize the specimen charging from the impinging … more

DTSA-II Reinvention of a Classic
Last Updated Date: 10/02/2012

The original NBS/NIH DTSA (Desktop Spectrum Analyzer) software was widely used in the x-ray microanalysis research community. The combination of … more

Depth Profiling of Drug Eluting Stent Coatings with Cluster SIMS
Last Updated Date: 10/02/2012

There is much excitement in the cardiology community about drug eluting stents (DES), a promising new treatment for coronary artery disease. A … more

Atomic Scale Imaging of Nanoscale Structures with Elemental Sensitivity in the NIST Titan 80-300
Last Updated Date: 10/02/2012

The characterization of CdSe/ZnS quantum dot structures has been carried out with compositionally sensitive imaging techniques utilizing the … more

Coupling Nanowire Chemisresistors with MEMS Microhotplate Gas Sensing Platforms
Last Updated Date: 10/02/2012

Recent advances in nanotechnology have yielded materials and structures that offer great potential for improving the sensitivity, selectivity, … more

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