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NIST Home > Bioscience & Health Programs and Projects 
 

Bioscience & Health Programs & Projects

(showing 106 - 120 of 147)
Computational Tool for Calculating Properties of Complex-Shaped Particles and Polymers
Last Updated Date: 04/16/2014

Many computational programs exist that are being used by industry for predicting properties of polymer composites, but their general predictive … more

Protein Preservation
Last Updated Date: 04/16/2014

Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in … more

Storage stability of Freeze-Dried Proteins
Last Updated Date: 04/15/2014

We are resolving critical measurement issues that prevent researchers from reliably predicting the chemical and physical storage stability of … more

Monoclonal Antibody MS Libraries
Last Updated Date: 10/21/2013

The National Institute of Standards and Technology is developing a mass spectral library of all identifiable components derived from the digestion … more

Microcalorimetry of biopharmaceuticals
Last Updated Date: 09/19/2013

We are using calorimetry to probe several key aspects of biopharmaceuticals related to safety and efficacy. Microcalorimetry can be used to … more

Optical/electrical particle measurement system
Last Updated Date: 09/16/2013

The sizing and counting of subvisible particles in the size range 2 µm to 100 µm is an essential component of product quality assurance in … more

Surrogate protein particle standards
Last Updated Date: 09/10/2013

Protein-based drugs can degrade by aggregation into micrometer-sized particles.  Such particles, although only a minute fraction of the total … more

Chinese hamster ovary (CHO) cell line authentication
Last Updated Date: 09/09/2013

The misidentification of cell lines has been a problem in the scientific community for the past 50 years. Methods are now in place to genotype … more

Tandem Mass Spectral Library
Last Updated Date: 07/10/2013

The National Institute of Standards and Technology is responsible for an evaluated, tandem mass spectral library as an extension of the … more

Collagen Films Protocol
Last Updated Date: 05/08/2013

Background: Collagen type 1 is the most prevalent extracellular protein in connective tissue, and is part of the family of collagens that are … more

Digital PCR
Last Updated Date: 04/26/2013

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR … more

SRM for Huntington CAG Repeat
Last Updated Date: 03/15/2013

Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by … more

DNA Profiling Standard Reference Materials
Last Updated Date: 03/15/2013

NIST has produced several PCR-based DNA Profiling Standard Reference Materials (SRMs) for the forensic community. The primary uses of these … more

Genome in a Bottle Consortium
Last Updated Date: 03/15/2013

NIST has organized the "Genome in a Bottle Consortium" to develop the reference materials, reference data, and reference methods needed to assess … more

Development of a Collagen Fibril Reference Material for Reproducible Cell Response
Last Updated Date: 01/11/2013

An important determinant of cellular response to drugs and toxins is the chemical and physical nature of the extracellular matrix (ECM) to which … more

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