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Bioscience & Health Programs & Projects

(showing 61 - 75 of 133)
Nanoplasmonics and Three-Dimensional Plasmonic Metamaterials
Last Updated Date: 06/28/2013

Metamaterials are tailor-made photonic composites--combinations of materials designed to achieve optical properties not seen in nature. The … more

Collagen Films Protocol
Last Updated Date: 05/08/2013

Background: Collagen type 1 is the most prevalent extracellular protein in connective tissue, and is part of the family of collagens that are … more

Digital PCR
Last Updated Date: 04/26/2013

Digital PCR (dPCR) is a method used to quantify nucleic acids (DNA, RNA, cDNA). At NIST we are using microfluidic and emulsion-based dPCR … more

Microfluidic Synthesis of Nanoparticles
Last Updated Date: 04/16/2013

Liposomes are nanometer-sized spherical vesicles made of phospholipids similar to those found in cell membranes of living organisms. Traditional … more

DNA Biometrics
Last Updated Date: 03/15/2013

There is ongoing interest in utilizing DNA typing methods for biometric purposes. Forensic DNA typing using STR markers has been performed in the … more

SRM for Huntington CAG Repeat
Last Updated Date: 03/15/2013

Huntington disease is a neurodegenerative disease of midlife onset that produces choreic movements and cognitive decline, often accompanied by … more

DNA Profiling Standard Reference Materials
Last Updated Date: 03/15/2013

NIST has produced several PCR-based DNA Profiling Standard Reference Materials (SRMs) for the forensic community. The primary uses of these … more

Genome in a Bottle Consortium
Last Updated Date: 03/15/2013

NIST has organized the "Genome in a Bottle Consortium" to develop the reference materials, reference data, and reference methods needed to assess … more

Development of Standard Reference Materials for Vitamins B6 and B12 in Human Serum
Last Updated Date: 03/15/2013

Vitamins are essential to normal functioning of the human body because they serve as co-factors for important biological processes. Deficiencies … more

Development of Proteomics-Based Methods for Protein Quantification
Last Updated Date: 03/13/2013

NIST is developing methods for the quantification of clinically-relevant protein biomarkers by mass spectrometry. Some methods are intended to … more

Improving Measurement Quality in Clinical Proteomics
Last Updated Date: 03/13/2013

Through collaboration with academic and government institutes, NIST is critically evaluating and attempting to improve measurement quality in … more

Development of Reference Methods and Reference Materials for the Determination of Cardiac Troponin I in Human Serum
Last Updated Date: 03/13/2013

Cardiac troponin I (cTnI) is considered the 'gold standard' for the diagnosis of myocardial infarction and the assessment of cardiac damage. Yet … more

Development of a Reference Measurement Procedure for C-Reactive Protein in Human Serum
Last Updated Date: 03/13/2013

C-reactive protein (CRP) levels in serum or plasma have been used as an indicator of inflammation and infection. Recent evidence also suggests … more

Development of an Amino Acid (in Solution) Standard Reference Material
Last Updated Date: 03/13/2013

Amino acids are the sequential components of proteins and many are essential to our physiological well-being. Their quantification by the … more

Chromatographic Separation of Unfolded Proteins for Protein Quantification
Last Updated Date: 03/13/2013

NIST is developing methods for the quantification of protein biomarkers by mass spectrometry (MS). Stable isotope labeling of proteins/peptides … more

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