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Bioscience & Health Programs & Projects

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Development of Reference Methods and Reference Materials for Proteins
Last Updated Date: 01/13/2015

A number of proteins show promise as potential markers of health or disease, and commercial assays are being developed for these proteins. For … more

Expression of Stable Isotopically Labeled Proteins for Use as Internal Standards for Mass Spectrometric Quantitation of Clinical Protein Biomarkers
Last Updated Date: 01/06/2015

Proteins are of significant interest as potential indicators (biomarkers) of health or disease. Clinical methods employed to measure these … more

Advanced Materials Metrology
Last Updated Date: 12/12/2014

In this project we measure the fundamental electrical properties of materials from bulk to nanoscale from 1 MHz to 0.3 THz. Understanding the … more

HDX-MS for Biopharmaceutical Analysis
Last Updated Date: 12/08/2014

This project applies hydrogen/deuterium exchange mass spectrometry (HDX-MS) for determining the dynamical structure of therapeutic antibodies, … more

Cytomegalovirus Standard Reference Material
Last Updated Date: 12/08/2014

**Update** As of the Summer of 2013, we discontinued distribution of SRM 2366 Cytomegalovirus (CMV) for DNA Measurements. In April of 2014, … more

Certification of a Standard Reference Material for BK viral load
Last Updated Date: 12/05/2014

BK virus (BKV), originally described in 1971 [1],  is a 5kb polyomavirus which shares roughly 75% of its DNA sequence with JC virus (JCV).  Nearly … more

Biomagnetic Imaging Standards and Microsystems
Last Updated Date: 12/02/2014

The Magnetics Group's program in biomagnetic imaging standards and microsystems develops calibration standards and new types of magnetic contrast … more

Bioimaging
Last Updated Date: 12/01/2014

Our goal is to develop methods and materials for imaging-based characterization of molecular signatures that occur during cellular proliferation, … more

Biomanufacturing
Last Updated Date: 10/09/2014

Protein drugs are the top selling pharmaceuticals worldwide, a hundred billion dollar industry, but also the fastest growing category of health … more

Nanotube Metrology
Last Updated Date: 10/02/2014

Nanotube metrology improvement is a significant effort in the Particles, Tubes and Colloids project dedicated to improving the measurement methods … more

Optical Spectroscopy of Nanostructures
Last Updated Date: 09/30/2014

Understanding the underlying chemistry and physics of nanomaterials, including noble and transition metallic nanoparticles, carbon nanotubes, and … more

Metrology for Advanced Bioelectronics
Last Updated Date: 09/29/2014

We are developing electronic chip-based technology for DNA and protein analysis for industry. This research will help revolutionize health care, … more

Nanoparticle Manipulation Metrology
Last Updated Date: 09/25/2014

We are advancing the measurement of dimension and function of engineered nanoparticles for biomedical research, manufacturing, and environmental … more

Clinical Quality Assurance Program
Last Updated Date: 09/16/2014

The National Institute of Standards and Technology (NIST) has established a Clinical Quality Assurance Program (ClinQAP) to support the … more

Fluorescence Microscope Benchmarking
Last Updated Date: 08/25/2014

We have made available a method to characterize a fluorescence microscope's performance by benchmarking the detection threshold, saturation and … more

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