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Bioscience & Health Programs & Projects

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Protein Preservation
Last Updated Date: 04/16/2014

Our goal is to address critical measurement issues that exist regarding chemical and physical stability of biomacromolecules (proteins and DNA) in … more

Storage stability of Freeze-Dried Proteins
Last Updated Date: 04/15/2014

We are resolving critical measurement issues that prevent researchers from reliably predicting the chemical and physical storage stability of … more

Development of Reference Methods and Reference Materials for the Determination of Hormones in Human Serum
Last Updated Date: 01/08/2014

Hormones are chemical messengers that regulate many life functions, and deviations from normal levels can indicate serious health problems. … more

Fatty Acids in Human Serum and Plasma Quality Assurance Program
Last Updated Date: 01/07/2014

The National Institute of Standards and Technology (NIST) and the National Institutes of Health (NIH) Office of Dietary Supplements (ODS) have … more

Resonating Platforms for Nanomaterial Analysis
Last Updated Date: 12/19/2013

Our goal is to develop quartz crystal microbalance (QCM) instrumentation and advanced oscillators with enhanced sensitivity to … more

Monoclonal Antibody MS Libraries
Last Updated Date: 10/21/2013

The National Institute of Standards and Technology is developing a mass spectral library of all identifiable components derived from the digestion … more

Microcalorimetry of biopharmaceuticals
Last Updated Date: 09/19/2013

We are using calorimetry to probe several key aspects of biopharmaceuticals related to safety and efficacy. Microcalorimetry can be used to … more

Optical/electrical particle measurement system
Last Updated Date: 09/16/2013

The sizing and counting of subvisible particles in the size range 2 µm to 100 µm is an essential component of product quality assurance in … more

Protein rheology measurements
Last Updated Date: 09/16/2013

Therapeutic protein solutions are highly concentrated during manufacturing purification processes and in finished dosage. At such concentrations, … more

Surrogate protein particle standards
Last Updated Date: 09/10/2013

Protein-based drugs can degrade by aggregation into micrometer-sized particles.  Such particles, although only a minute fraction of the total … more

Chinese hamster ovary (CHO) cell line authentication
Last Updated Date: 09/09/2013

The misidentification of cell lines has been a problem in the scientific community for the past 50 years. Methods are now in place to genotype … more

Optical medical imaging
Last Updated Date: 08/02/2013

The Optical Medical Imaging program was established to advance the application of optical imaging in surgical, clinical, and medical practices. … more

Hyperspectral Image Projector (HIP)
Last Updated Date: 08/02/2013

Detecting climate change with remote sensing instruments, providing state-of-the-art surveillance imagery for security and defense, or getting the … more

Peptide Mass Spectral Libraries
Last Updated Date: 07/23/2013

The National Institute of Standards and Technology is developing a peptide mass spectral library as an extension of the NIST/EPA/NIH Mass Spectral … more

Tandem Mass Spectral Library
Last Updated Date: 07/10/2013

The National Institute of Standards and Technology is responsible for an evaluated, tandem mass spectral library as an extension of the … more

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